| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
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| 영문 | Electric convulsive therapy(ECT) | 한글 | 전기경련요법 |
|---|---|---|---|
| 설명 | 뇌에 전기 자극을 주어 인위적으로 경련을 유발함으로써 정신 병을 치료하는 방법. 전기쇼크요법(electroshock therapy)이라고도 한다. 1938년에 이탈리아의 체를레티와 비니에 의해 시작되었다. 작용기전은 확실치 않으나 뇌의 신진대사, 생화학 및 효소 등에 변화를 일으킨다는 생물학적, 생화학적 학설이 유력하다. 적응증으로 가장 효과적인 병은 우울증으로 특히 여성에서 갱년기에 호발하는 갱년기 우울증, 우울증과 조증(아주 기분이 좋은 상태가 지속되는 정신병)이 일정한 주기를 두고 반복하는 조울증에 잘 쓰이며, 80~90%에서 효과가 있다. |
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| PCD | pacer-cardioverter-defibrillator; papillary collecting duct; paraneoplastic cerebellar degeneration;... |
|---|---|
| PCS | palliative care service; Patient Care System; patterns of care study; pelvic congestion syndrome; ph... |
| PDPD | prolonged-dwell peritoneal dialysis |
| PFUO | prolonged fever of unknown origin |
| PPIE | prolonged postictal encephalopathy |
| sleep terror | A disorder allied to nightmare, occurring in children, in which the child awakes screaming with fright, the distress persisting for a time during a state of saemiconsciousness. Synonym: pavor nocturnus, sleep terror. (05 Mar 2000) |
|---|---|
| delta sleep-inducing peptide | <chemical> A nonapeptide that is found in neurons, peripheral organs, and plasma. This neuropeptide induces mainly delta sleep in mammals. In addition to sleep, the peptide has been observed to affect electrophysiological activity, neurotransmitter levels in the brain, circadian and locomotor patterns, hormonal levels, psychological performance, and the activity of neuropharmacological drugs including their withdrawal. Chemical name: Delta sleep-inducing peptide (12 Dec 1998) |
| obstructive sleep apnoea | A form of sleep apnoea which occurs as the result of a physical occlusion of the oropharyngeal airway during sleep. (27 Sep 1997) |
| electric sleep | A condition of convulsions and unconsciousness induced by the passage of an electric current through the brain. (05 Mar 2000) |
| twilight sleep | Formerly a method of producing sleep for delivery by a combination of morphine and scopolamine. (05 Mar 2000) |
| light sleep | A condition of half sleep. Synonym: light sleep. Origin: dys-+ G. Nystaxis, drowsiness (05 Mar 2000) |
| acupuncture therapy | Treatment of disease by inserting needles along specific pathways or meridians. The placement varies with the disease being treated. Heat or moxibustion and acupressure may be used in conjunction. (12 Dec 1998) |
| adjuvant therapy | <oncology, pharmacology> Treatment that is added to increase the effectiveness of a primary treatment. In cancer, adjuvant treatment usually refers to chemotherapy, hormonal therapy or radiation therapy after surgery to increase the likelihood of killing all cancer cells. (14 May 1997) |
| alternative therapy | A term given to nonconventional therapy usually given by persons who do not have a medical qualification. (16 Dec 1997) |
| analytic therapy | Short term for psychoanalytic therapy. (05 Mar 2000) |
| Antibody Directed Enzyme Prodrug Therapy | <pharmacology> A method for targeting a drug to a specific tissue, in which the targeting agent and the drug are administered separately. The drug is designed to be inactive (a prodrug) until it is converted by an enzyme, which is the targeting agent. The enzyme is coupled to an antibody that directs it to the tissue of interest. When the enzyme arrives at the tissue, the prodrug is activated only at that site, sparing other tissues from potentially toxic side effects. Acronym: ADEPT (14 Nov 1997) |
| anticoagulant therapy | The use of anticoagulant drugs to reduce or prevent intravascular or intracardiac clotting. (05 Mar 2000) |
| antisense therapy | Use of antisense DNA for the inhibition of translation of a specific gene product for therapeutic purposes. (05 Mar 2000) |
| art therapy | The use of art as an adjunctive therapy in the treatment of neurological, mental, or behavioural disorders. (12 Dec 1998) |
| autoserum therapy | Therapy with serum obtained from the patient's own blood. (05 Mar 2000) |