| PM | after death (Lat. post mortem); after noon [Lat. post meridiem]; mean pressure; pacemaker; pantomogr... |
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| DCS | decompression sickness; dense canalicular system; diffuse cortical sclerosis; dorsal column stimulat... |
| DDD | AV universal [pacemaker]; defined daily dose; degenerative disc disease; dehydroxydinaphthyl disulfi... |
| DFECT | dense fibroelastic connective tissue |
| DIDD | dense intramembranous deposit disease |
| platelet function disorders | <haematology> Platelet function can be affected by a number of different disease processes including polycythaemia vera, leukaemia, myelofibrosis, renal failure, multiple myeloma and some medications (for example penicillins, salicylates, phenothiazines). Disturbed blood clotting can be manifested by: easy bruising, bleeding gums, nosebleeds, abnormal vaginal bleeding, rectal bleeding, skin rash, vomiting blood, coughing up blood or blood in the urine. A measure of bleeding time and coagulation profile will be part of the evaluation. (31 Dec 1997) |
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| platelet glycoprotein gpib-ix complex | Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury. It is composed of three polypeptides, gpib alpha, gpib beta, and gpix. Glycoprotein ib functions as a receptor for von willebrand factor and for thrombin. Congenital deficiency of the gpib-ix complex results in bernard-soulier syndrome. The platelet glycoprotein gpv associates with gpib-ix and is also absent in bernard-soulier syndrome. (12 Dec 1998) |
| platelet glycoprotein gpiib-iiia complex | Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. The complex is an integrin which recognises the arginine-glycine-aspartic acid (rgd) sequence present on several adhesive proteins. As such, it is a receptor for fibrinogen, von willebrand factor, fibronectin, vitronectin, and thrombospondin. A deficiency of gpiib-iiia results in glanzmann's thrombasthenia. (12 Dec 1998) |
| platelet membrane glycoproteins | Surface glycoproteins on platelets which have a key role in haemostasis and thrombosis such as platelet adhesion and aggregation. Many of these are receptors. (12 Dec 1998) |
| platelet storage pool deficiency | A group of disorders characterised by a decrease or lack of platelet dense bodies in which the releasable pool of adenine nucleotides and 5ht are normally stored. (12 Dec 1998) |
| platelet thrombosis | Thrombosis due to an abnormal accumulation of platelets. (05 Mar 2000) |
| platelet tissue factor | <haematology> Traditional name for substance in plasma that converts prothrombin to thrombin. Now known not to be a single substance. (See thrombin). (18 Nov 1997) |
| platelet transfusion | The transfer of blood platelets from a donor to a recipient or reinfusion to the donor. (12 Dec 1998) |
| low affinity platelet factor IV | Cytokine, produced from platelet basic protein, that acts as a growth factor. (18 Nov 1997) |
| low platelet count | <haematology> An abnormally low platelet count. Normal platelet counts are 150,000-400,000 per cubic millimetre. Those with low platelet counts may exhibit haematuria, haematemesis, easy bruising, bleeding gums, melena (blood in stools), prolonged menses or nosebleeds. Spontaneous intracranial haemorrhage can occur with platelet counts of 10-15,000 (or less). (27 Sep 1997) |
| acetone body | <biochemistry> Any of the three compounds created by acetyl coenzyme A (acetoacetate, hydroxybutyrate, and acetone) which are water-soluble cellular fuels normally exported by the liver. They can build up in the blood and body tissues because of starvation, untreated diabetes mellitus, or other disorders that interfere with carbohydrate metabolism. The body rids itself of ketones mainly through urine, but it rids itself of acetone through the lungs, which gives the breath a characteristic fruity odour. If ketones build up in the body long enough, they cause serious illness and coma (see ketoacidosis.) (09 Oct 1997) |
| acute inclusion body encephalitis | The most common acute encephalitis, caused by HSV-1; affects persons of any age; preferentially involves the inferomedial portions of the temporal lobe and the orbital portions of the frontal lobes; pathologically, severe haemorrhagic necrosis is present along with, in the acute stages, intranuclear eosinophilic inclusion bodies in the neurons and glial cells. Synonym: acute inclusion body encephalitis, herpes encephalitis. (05 Mar 2000) |
| adrenal body | See adrenal gland. (12 Dec 1998) |
| alveolar body | That portion of bone in either the maxilla or the mandible which surrounds and supports the teeth. (12 Dec 1998) |
| amygdaloid body | Almond-shaped group of basal nuclei anterior to the inferior horn of the lateral ventricle of the brain, within the temporal lobe. The amygdala is part of the limbic system. (12 Dec 1998) |