| KBG | syndrome of multiple abnormalities designated with the original patient's initials |
|---|---|
| MIKA | minor karyotype abnormalities |
| MOMO | macrosomia-obesity-macrocephaly-ocular abnormalities [syndrome] |
| NAA | N-acetyl aspartate; naphthaleneacetic acid; neutral amino acid; neutron activation analysis; neutrop... |
| WAGR | Wilms tumor, aniridia, genitourinary abnormalities, and mental retardation |
| familial lipoprotein lipase deficiency | An rare inherited disorder where there is a deficiency of an enzyme (lipoprotein lipase) which breaks down fat molecules, causing the accumulation of fats or lipoproteins in the blood. Symptoms in infancy include abdominal pain (appears as if its colic), failure to thrive and skin lesions (xanthomas). (27 Sep 1997) |
|---|---|
| familial lipoprotein lipase inhibitor | An inhibitor found in certain individuals that inhibits lipoprotein lipase resulting in accumulation of chylomicrons, VLDL, and triacylglycerols; similar in symptoms to familial lipoprotein lipase deficiency. (05 Mar 2000) |
| lipoprotein | <biochemistry> An important class of serum proteins in which a spherical hydrophobic core of triglycerides or cholesterol esters surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Classified according to density: chylomicrons, large low density particles, very low density, low density and high density species. Important in lipid transport, especially cholesterol transport in the blood stream. Abnormalities in lipoprotein metabolism have been implicated in certain heart diseases. (13 Nov 1997) |
| lipoprotein(a) | A family of lipoprotein particles varying in density and size depending on the protein-lipid ratio and the protein composition. These particles consist of apolipoprotein b-100 covalently linked to apolipoprotein-a by one or two disulfide bonds. There is a correlation between high plasma levels of this lipoprotein and increased risk for atherosclerotic cardiovascular disease. (12 Dec 1998) |
| lipoprotein(a) hyperlipoproteinaemia | Elevated levels of lipoprotein(a) in the serum; associated with an increased risk of coronary disease. (05 Mar 2000) |
| lipoprotein-associated coagulation inhibitor | Formerly known as anticonvertin; a protein that inhibits the extrinsic pathway of coagulation by binding to the tissue factor III-factor VII-Calcium-factor Xa complex. (05 Mar 2000) |
| lipoprotein electrophoresis | Electrophoretic separation of plasma lipoproteins. (05 Mar 2000) |
| lipoprotein lipase | <enzyme> An enzyme of the hydrolase class that catalyses the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinaemia type I. Chemical name: Triacylglycero-protein acylhydrolase Registry number: EC 3.1.1.34 (12 Dec 1998) |
| lipoprotein lipase deficiency, familial | A rare familial condition characterised by massive chylomicronaemia and decreased levels of other lipoproteins. It is due to deficiency of lipoprotein lipase, an alkaline triglyceride hydrolase which catalyses an important step in the extrahepatic removal of triglyceride-rich lipoproteins from the blood. (12 Dec 1998) |
| lipoprotein Lp(a) | A lipoprotein composed of an LDL particle combined with an additional protein, Lp(a) specific protein; elevated levels have been identified as a risk factor for coronary artery disease. (05 Mar 2000) |
| lipoprotein polymorphism | Heritable variations in low density beta-lipoproteins; the variant lipoproteins exhibit different antigenic and chemical properties when compared with normal lipoproteins. (05 Mar 2000) |
| lipoprotein-x | An abnormal lipoprotein which is present in large amounts in individuals suffering from obstructive liver diseases. It exists as a bilayer vesicle of equimolar phospholipids and unesterified cholesterol containing small amounts of plasma proteins (mainly albumin) in its internal aqueous compartment together with some apolipoproteins adsorbed on its surface. Separates with ldl by ultracentrifugation. (12 Dec 1998) |
| low density lipoprotein | <biochemistry> A lipoprotein substances (combination of a fat and a protein) which acts as a carrier for cholesterol and fats in the bloodstream. High levels of low density lipoprotein are considered a positive risk factor for the development of coronary artery disease. Less than 130 mg/dl is desirable, 130 to 159 mg/dl is borderline high, over 160 is considered high. Acronym: LDL (10 Jan 1998) |
| low density lipoprotein receptor | <biochemistry> A cell surface protein that mediates the endocytosis of low density lipoprotein by cells. Genetic defects in low density lipoprotein receptors lead to abnormal serum levels of low density lipoprotein and hypercholesterolaemia. (16 Mar 1998) |
| low-density lipoprotein receptors | Receptors on the surface of cells, especially liver cells, which bind to low density lipoprotein and promote clearance of LDL from the plasma. (05 Mar 2000) |