| testosterone-oestrogen-binding globulin | A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Changes in its concentration significantly affect the ratio of unbound (biologically active) testosterone to estradiol in plasma. (12 Dec 1998) |
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| tetanus immune globulin | <protein> A protein antibody to tetanus toxin, given as passive immunity for those lacking any prior tetanus vaccination. (27 Sep 1997) |
| thyroid binding globulin | <protein> Thyroid binding globulin (TBG) is a plasma protein which binds the majority of thyroid hormone in the bloodstream. Bound thyroid hormone is inactive, only the unbound fraction (0.3%) is considered active. Birth control pills and pregnancy can lead to increased TBG levels in the plasma. Androgens can decrease TBG levels in the plasma. (27 Sep 1997) |
| thyroxine-binding globulin | An alpha-globulin of blood with a strong binding affinity for thyroxine; triiodothyronine is bound to it much less firmly; a deficiency or excess of this protein may occur as a rare benign X-linked disorder. Synonym: thyroxine-binding protein. (05 Mar 2000) |
| zoster immune globulin | A globulin fraction of pooled plasma from individuals who have recovered from herpes zoster; used prophylactically and therapeutically for varicella. (05 Mar 2000) |
| antihemophilic plasma | Human plasma in which the labile antihemophilic globulin component, present in fresh plasma, has been preserved; it is used to temporarily relieve dysfunction of the haemostatic mechanism in haemophilia. (05 Mar 2000) |
| apical plasma membrane | <cell biology> The term used for the cell membrane on the apical (inner or upper) surface of transporting epithelial cells. This region of the cell membrane is separated, in vertebrates, from the baso lateral membrane by a ring of tight junctions that prevents free mixing of membrane proteins from these two domains. (18 Nov 1997) |
| basolateral plasma membrane | <cell biology> The plasma membrane of epithelial cells that is adjacent to the basal lamina or the adjoining cells of the sheet. Differs both in protein and phospholipid composition from the apical plasma membrane from which it is isolated by tight junctions (zonula occludentes). (18 Nov 1997) |
| beam-plasma reaction | <radiobiology> Fusion reaction which occurs from the collision of a fast beam ion with a thermal plasma ion. (09 Oct 1997) |
| bean-shaped plasma | <radiobiology> A toroidal plasma indented on the inboard side (the side with the donut hole), that results in additional stability to ballooning modes. Moderate indentation may provide access to the second-stability region (high beta). (13 Nov 1997) |
| blood plasma | <haematology> Acellular fluid in which blood cells are suspended. Serum obtained by defibrinating plasma (plasma derived serum) lacks platelet released factors and is less suitable to support the growth of cells in culture. (13 Oct 1997) |
| blood plasma fractions | Portions of the blood plasma as separated by electrophoresis or other technique. (05 Mar 2000) |
| rapid plasma reagin | <investigation> The rapid plasma reagin test is similar to the VDRL test for diagnosing syphilis. This blood test is designed to detect an antibody substance in the bloodstream when syphilis infection is present. Early syphilis infections may be RPR negative. See: VDRL (17 Dec 1997) |
| rapid plasma reagin test | A group of serologic test's for syphilis in which unheated serum or plasma is reacted with a standard test antigen containing charcoal particles; positive test's yield a flocculation. A modification, called the RPR (circle) card test, is widely used as a screening test. Synonym: RPR test. (05 Mar 2000) |
| renal plasma flow | <physiology> The amount of plasma that perfuses the kidneys per unit time, approximately 10% greater than effective renal plasma flow. It should be differentiated from the renal blood flow which refers to the total volume of blood flowing through the renal vasculature, while the renal plasma flow refers to the rate of plasma flow. (12 Dec 1998) |