| hydatidiform mole | <gynaecology, oncology, tumour> A relatively rare mass or tumour that can form within the uterus at the beginning of a pregnancy. The cause of hydatidiform mole is unknown. Symptoms include vaginal bleeding, uterine growth, nausea and vomiting. Some hydatidiform moles may become malignant (cancerous) where they are referred to as a choriocarcinoma. Incidence: 1 in 1,500 births. (02 Jan 1998) |
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| hydatidiform mole, invasive | A tumour or tumour-like process invading the myometrium, and characterised by trophoblastic hyperplasia and persistence of placental villous structures. It commonly results from complete hydatidiform mole but may do so from partial hydatidiform mole. Invasive mole may metastasize but it does not exhibit the progression of a true cancer, and it may regress spontaneously. (holland et al., cancer medicine, 3d ed, p1691) (12 Dec 1998) |
| hydatiform mole | <radiology> Trophoblastic proliferation with avascularity of chorionic villi, marked oedema and enlargement of chorionic villi, severe eclampsia prior to 24 weeks, 1st trimester bleeding, abnormal elevation of beta-hCG, passing grapelike vesicles per vagina, uterus large for dates (50%), hyperechoic intrauterine tissue interspersed with numerous punctate hypoechoic areas (hydropic villi), in 25% atypical appearance: large hyperechoic areas (blood clots) and areas of cystic degeneration; resembles incomplete abortion, thick hyperechoic rim around central anechoic zone, bilateral theca lutein cysts (18-37%) see also: gestational trophoblastic disease, hydatiform mole: types (12 Dec 1998) |
| hydatiform mole: types | <radiology> Complete/classical mole, fertilization of an empty egg; diploid karyotype (paternal XX), no foetal parts; no chorionic membrane, 20% malignant complete mole with coexistent foetus (2%), molar degeneration of an identical twin partial mole, areas of molar change alternating with normal chorionic villi, triploid karyotype (66% XXY; 33% XXX), early onset of preeclampsia, foetal structures present (e.g., placenta), no malignant potential see: hydatiform mole (12 Dec 1998) |
| spider mole | spider angioma |
| nevus, pigmented | A nevus containing melanin. The term is usually restricted to nevocytic nevi (round or oval collections of melanin-containing nevus cells occurring at the dermoepidermal junction of the skin or in the dermis proper) or moles, but may be applied to other pigmented nevi. (12 Dec 1998) |
| synovitis, pigmented villonodular | Outgrowths of synovial membrane composed of villi and fibrous nodules characterised histologically by haemosiderin- and lipid-containing macrophages and multinucleated giant cells. It usually occurs in the knee. (12 Dec 1998) |
| invasive mole | chorioadenoma destruens |
| false mole | <gynaecology> An intrauterine polyp. (05 Mar 2000) |
| fleshy mole | A uterine mass occurring after foetal death and consisting of blood clots, foetal membranes, and placenta. Synonym: blood mole, carneous mole. (05 Mar 2000) |