| ETD | eustachian tube dysfunction |
|---|---|
| FAD | familial Alzheimer dementia; familial autonomic dysfunction; fetal activity-acceleration determinati... |
| LVD | left ventricular dysfunction |
| MBD | Marchiafava-Bignami disease; Mental Deterioration Battery; methylene blue dye; minimal brain damage;... |
| MCD | magnetic circular dichroism; mast-cell degranulation; mean cell diameter; mean of consecutive differ... |
| malignancy and immunodeficiency | <radiology> High risk of malignancy (especially lymphoma/leukaemia, GI tumours): X-linked agammaglobulinaemia (Bruton's), common variable immunodeficiency, severe combined immunodeficiency (SCID kids), ataxia-telangectasia, Wiscott-Aldrich syndrome, selective IgA deficiency (12 Dec 1998) |
|---|---|
| cellular immunodeficiency with abnormal immunoglobulin synthesis | An ill-defined group of sporadic disorders of unknown cause, occurring in both males and females and associated with recurrent bacterial, fungal, protozoal, and viral infections; there is thymic hypoplasia with depressed cellular (T-lymphocyte) immunity combined with defective humoral (B-lymphocyte) immunity, although immunoglobulin levels may be normal. Synonym: Nezelof syndrome, Nezelof type of thymic alymphoplasia. (05 Mar 2000) |
| combined immunodeficiency | <immunology> Congenital immunodeficiency with thymic agenesis, lymphocyte depletion and hypogammaglobulinaemia: both cellular and humoral immune systems are affected and life expectancy is low unless marrow transplantation is successful. (18 Nov 1997) |
| combined immunodeficiency syndrome | <syndrome> A serious primary immunodeficiency affecting both T and B-cells. (05 Mar 2000) |
| common variable immunodeficiency | Heterogeneous group of immunodeficiency syndromes characterised by hypogammaglobulinaemia of most isotypes, variable B-cell defects, and the presence of recurrent bacterial infections. (12 Dec 1998) |
| congenital severe combined immunodeficiency | Disease, one form of which is caused by the lack of a transcription factor required for expression of HLA class II genes. (18 Nov 1997) |
| murine acquired immunodeficiency syndrome | <syndrome> Acquired defect of cellular immunity that occurs in mice infected with mouse leukaemia viruses (mulv). The syndrome shows striking similarities with human aids and is characterised by lymphadenopathy, profound immunosuppression, enhanced susceptibility to opportunistic infections, and B-cell lymphomas. (12 Dec 1998) |
| secondary immunodeficiency | Immunodeficiency in which there is no evident defect in the lymphoid tissues, but rather hypercatabolism or loss of immunoglobulins such as occurs in familial idiopathic hypercatabolic hypoproteinaemia or in defects associated with the nephrotic syndrome. Synonym: secondary agammaglobulinaemia, secondary antibody deficiency, secondary hypogammaglobulinaemia. (05 Mar 2000) |
| human immunodeficiency virus | <virology> A type of retrovirus (human immunodeficiency virus) that is responsible for the fatal illness acquired immunodeficiency syndrome. Two strains have been identified. Type 1: the retrovirus recognised as the agent that induces AIDS. Type 2: a virus closely related to HIV-1 that also leads to immune suppression. HIV-2 is not as virulent as HIV-1 and is epidemic only in West Africa. Acronym: HIV (11 Nov 1997) |
| severe combined immunodeficiency | Group of rare congenital disorders characterised by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. It is inherited as an x-linked or autosomal recessive defect. About half of the patients with autosomal recessive scid are deficient in the enzyme adenosine deaminase. (12 Dec 1998) |
| simian acquired immunodeficiency syndrome | <syndrome> Acquired defect of cellular immunity that occurs naturally in macaques infected with srv serotypes, experimentally in monkeys inoculated with srv or mason-pfiser monkey virus (mpmv), or in monkeys infected with siv. (12 Dec 1998) |
| simian immunodeficiency virus | <virology> A retrovirus found in monkeys that is closely related to HIV. (09 Oct 1997) |
| immunodeficiency | Inabillity to mount a normal immune response. Immunodeficiency can be due to a genetic disease or acquired as in aids due to HIV. (12 Dec 1998) |
| immunodeficiency disorders | <radiology> B-cell (antibody) deficiency: high-grade pathogens: pneumococcus, strep, H. Flu, chronic sinopulmonary disease, usual survival to adulthood, T-cell (cellular) deficiency: low-grade pathogens: fungi, viruses, Pneumocystic, growth retardation, diarrhoea, delayed anergy, short life-span, susceptible to graft vs. Host (GvH) disease, e.g.: DiGeorge syndrome, Nezelhof syndrome Note: increased risk of malignancy (12 Dec 1998) |
| immunodeficiency syndrome | <syndrome> An immunological deficiency or disorder, of which the chief symptom is an increased susceptibility to infection, the pattern of susceptibility being dependent upon the kind of deficiency. See: immunodeficiency. (05 Mar 2000) |