| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
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| 영문 | Electric convulsive therapy(ECT) | 한글 | 전기경련요법 |
|---|---|---|---|
| 설명 | 뇌에 전기 자극을 주어 인위적으로 경련을 유발함으로써 정신 병을 치료하는 방법. 전기쇼크요법(electroshock therapy)이라고도 한다. 1938년에 이탈리아의 체를레티와 비니에 의해 시작되었다. 작용기전은 확실치 않으나 뇌의 신진대사, 생화학 및 효소 등에 변화를 일으킨다는 생물학적, 생화학적 학설이 유력하다. 적응증으로 가장 효과적인 병은 우울증으로 특히 여성에서 갱년기에 호발하는 갱년기 우울증, 우울증과 조증(아주 기분이 좋은 상태가 지속되는 정신병)이 일정한 주기를 두고 반복하는 조울증에 잘 쓰이며, 80~90%에서 효과가 있다. |
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| AMBER | advanced multiple-beam equalization radiography |
|---|---|
| BEAM | brain electrical activity monitoring |
| BEV | baboon endogenous virus; beam's eye view |
| EB | elective abortion; electron beam; elementary body; emotional behavior; endometrial biopsy; epidermol... |
| EBCT | electron-beam computed tomography |
| signal recognition particle receptor | Receptor for the signal recognition particle (SRP) found in the membrane of the endoplasmic reticulum. Also called docking protein. Heterodimeric, both protomers having GTP binding capacity, though dissimilar binding sites. Not until the complex of SRP, ribosome, message and nascent polypeptide chain binds to the SRP receptor is the block to further chain elongation released and concurrently the SRP is released, leaving the ribosome attached to the endoplasmic reticulum membrane. Cotranslational transport of the polypeptide delivers it into the lumen of the ER. (18 Nov 1997) |
|---|---|
| submitochondrial particle | Formed by sonicating mitochondria. Small vesicles in which the inner mitochondrial membrane is inverted to expose the innermost surface. (18 Nov 1997) |
| dane particle | <virology> 42 nm spherical particle, the complete infective virion of hepatitis B containing a 27 nm core antigen. (27 Sep 1997) |
| defective interfering particle | An incomplete virus that is unable to replicate and interferes with replication of an infectious virus. (05 Mar 2000) |
| D.I. particle | <abbreviation> Defective interfering particle. (05 Mar 2000) |
| dressed particle | <radiobiology> A particle plus its associated neutralising Debye sphere. (09 Oct 1997) |
| intramembranous particle | <cell biology> Particles (or complementary pits) seen in freeze fractured membranes. The cleavage plane is through the centre of the bilayer and the particles are usually assumed to represent Integral membrane proteins (or polymers of such proteins). (18 Nov 1997) |
| either particle flux density | The particle fluence rate, or energy flux density, the energy fluence rate of intensity. Compare: fluence. (05 Mar 2000) |
| elementary particle interactions | The interactions of particles responsible for their scattering and transformations (decays and reactions). Because of interactions, an isolated particle may decay into other particles. Two particles passing near each other may transform, perhaps into the same particles but with changed momenta (elastic scattering) or into other particles (inelastic scattering). Interactions fall into three groups: strong, electromagnetic, and weak. (12 Dec 1998) |
| trapped-particle instability | <radiobiology> Slowly-growing class of instabilities driven by particles which cannot circulate freely in a toroidal system. See: banana orbit. (09 Oct 1997) |
| kappa particle | <microbiology> Gram-negative bacterial endosymbiont of Paramoecium spp., (Caedobacter taeniospiralis) that confers the killer trait, infected Paramoecium are resistant to the toxin liberated by infected forms. Killing activity is associated with the induction of defective phage in the endosymbiont, leading to the release of R bodies, coded for by the phage genome and apparently of mis assembled phage coat protein. (18 Nov 1997) |
| Zimmermann's elementary particle | <haematology> A discoid cell (3m diameter) found in large numbers in blood, important for blood coagulation and for haemostasis by repairing breaches (small breaks) in the walls of blood vessels. Platelet _ granules contain lysosomal enzymes, dense granules contain ADP (a potent platelet aggregating factor) and serotonin (a vasoactive amine). They also release platelet-derived growth factor which presumably contributes to later repair processes by stimulating fibroblast proliferation. Synonym: thrombocytes. (09 Oct 1997) |
| acupuncture therapy | Treatment of disease by inserting needles along specific pathways or meridians. The placement varies with the disease being treated. Heat or moxibustion and acupressure may be used in conjunction. (12 Dec 1998) |
| adjuvant therapy | <oncology, pharmacology> Treatment that is added to increase the effectiveness of a primary treatment. In cancer, adjuvant treatment usually refers to chemotherapy, hormonal therapy or radiation therapy after surgery to increase the likelihood of killing all cancer cells. (14 May 1997) |
| alternative therapy | A term given to nonconventional therapy usually given by persons who do not have a medical qualification. (16 Dec 1997) |