| Eisenmenger's defect | The combination of ventricular septal defect with pulmonary hypertension and consequent right-to-left shunt through the defect, with or without an associated overriding aorta. Synonym: Eisenmenger's defect, Eisenmenger's disease, Eisenmenger's tetralogy. (05 Mar 2000) |
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| endocardial cushion defect | <radiology> Persistence of primitive atrioventricular canal and anomalies of AV valves associated with: Down syndrome: in 25% of Trisomy 21 an ECD is present; in 45% of ECD Trisomy 21 is present, asplenia/polysplenia types: complete (AV canal), partial findings: gooseneck deformity on angiogram, increased pulmonary vascularity, enlarged pulmonary artery, enlarged RV, LV, RA; normal LA (secondary to atrial septal defect) (12 Dec 1998) |
| enzyme defect | A disorder resulting from a deficiency (or functional abnormality) of an enzyme. In 1902 Archibald Garrod first attributed a disease to an enzyme defect: an inborn error of metabolism. Today, newborns are routinely screened for certain enzyme defects such as PKU (phenylketonuria) and galactosaemia, an error in the handling (metabolism) of the sugar galactose. (12 Dec 1998) |
| fibrous cortical defect | A common 1 to 3 cm defect in the cortex of a bone, most commonly the lower femoral shaft of a child, filled with fibrous tissue. Nonosteogenic or nonossifying fibroma by convention refers to lesions greater than 3 cm in diameter. See: nonossifying fibroma. Synonym: nonosteogenic fibroma. (05 Mar 2000) |
| uterine filling defect | <radiology> Technical, bubble, blood clot, mucoid material, congenital fold, pseudoadhesions / ridging -- folds long axis, neoplasm, submucosal leiomyoma, adenoma, endometrial carcinoma, pregnancy-related, pregnancy, molar pregnancy, retained conceptus, polyp, septated uterus, synechiae, IUD, iatrogenic (post-op) (12 Dec 1998) |
| filling defect | Displacement of contrast medium by a space-occupying lesion in a radiographic study of a contrast-filled hollow viscus, such as a polyp on a barium enema; also applied to defects in the otherwise uniform distribution of radionuclide in an organ, such as a metastasis in the liver on a 99mTc-sulfur colloid scan. (05 Mar 2000) |
| filling defect in renal collecting system | <radiology> Common causes: transitional cell carcinoma, blood clot, lucent calculus (urate) less common causes: fungus ball, sloughed papilla, fibroepithelial polyp, invasion by hypernephroma, malakoplakia, vessel impression, metastases (12 Dec 1998) |
| lambdoid suture defect | <radiology> Well-defined lucent lesion, classically unilateral, associated with neurofibromatosis (12 Dec 1998) |
| luteal phase defect | Inadequate function of the corpus luteum that may prevent a fertilized egg from implanting in the uterus or may lead to early pregnancy loss. (09 Oct 1997) |
| alimentary tract | The passage leading from the mouth to the anus through the pharynx, oesophagus, stomach, and intestine. Synonym: alimentary canal, alimentary tract, digestive tube, tubus digestorius. (05 Mar 2000) |
| alimentary tract smear | A group of cytologic specimens containing material from the mouth (oral smear), oesophagus and stomach (gastric smear), duodenum (paraduodenal smear), and colon, obtained by specialised lavage techniques; used principally for the diagnosis of cancer of those areas. (05 Mar 2000) |
| anterior corticospinal tract | Uncrossed fibres forming a small bundle in the pyramidal tract. See: pyramidal tract. Synonym: tractus corticospinalis anterior, tractus pyramidalis anterior, anterior corticospinal tract, anterior pyramidal fasciculus, direct pyramidal tract, fasciculus corticospinalis anterior, fasciculus pyramidalis anterior, Turck's bundle, Turck's column, Turck's tract. (05 Mar 2000) |
| anterior pyramidal tract | Uncrossed fibres forming a small bundle in the pyramidal tract. See: pyramidal tract. Synonym: tractus corticospinalis anterior, tractus pyramidalis anterior, anterior corticospinal tract, anterior pyramidal fasciculus, direct pyramidal tract, fasciculus corticospinalis anterior, fasciculus pyramidalis anterior, Turck's bundle, Turck's column, Turck's tract. (05 Mar 2000) |
| anterior spinocerebellar tract | A bundle of fibres originating in the base of the posterior horn and zona intermedia throughout lumbosacral segments of the spinal cord, crossing to the opposite side and ascending in a peripheral position in the ventral half of the lateral funiculus. In its ascent through the rhombencephalon, the tract curves sharply dorsalward along the rostral border of the trigeminal motor nucleus, entering the cerebellum in a caudal direction over the dorsal surface of the superior cerebellar peduncle, and terminating as mossy fibres in the granular layer of the cortex of the cerebellar vermis. The bundle conveys proprioceptive and exteroceptive information largely from the opposite lower extremity. Synonym: tractus spinocerebellaris anterior, Gowers' column, Gowers' tract, ventral spinocerebellar tract. (05 Mar 2000) |
| anterior spinothalamic tract | The more anterior or ventral part of the spinothalamic tract that is involved in tactile sensation. See: spinothalamic tract. Synonym: tractus spinothalamicus anterior, ventral spinothalamic tract. (05 Mar 2000) |