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open-label trial A study in which both researchers and participants know what drug a person is taking and at what dose.
(09 Oct 1997)
open lung biopsy <investigation, procedure, surgery> A procedure which involves the removal of a small specimen of lung tissue for microscopic analysis via a surgical incision in the chest wall.
This test can be used to identify a variety of lung cancers, lung infections and lung diseases.
(21 Mar 1998)
open pneumothorax A free communication between the atmosphere and the pleural space either via the lung or through the chest wall.
Synonym: sucking wound.
(05 Mar 2000)
open pollination Pollination by wind, insects, or other natural mechanisms.
(09 Oct 1997)
open reading frame <molecular biology> A reading frame in a sequence of nucleotides in DNA that contains no termination codons and so can potentially translate as a polypeptide chain.
(18 Nov 1997)
open reading frames Reading frames where successive nucleotide triplets can be read as codons specifying amino acids and where the sequence of these triplets is not interrupted by stop codons.
(12 Dec 1998)
open reduction of fractures Reduction by manipulation of bone, after incision in skin and muscle over the site of the fracture.
(05 Mar 2000)
open skull fracture A fracture with laceration of overlying scalp and/or mucous membrane.
Synonym: compound skull fracture.
(05 Mar 2000)
open system A system that exchanges energy and materials with the outside environment.
(09 Oct 1997)
open tuberculosis Pulmonary tuberculosis, tuberculous ulceration, or other form in which the tubercle bacilli are present in the excretions or secretions; in the lung, usually the result of cavity formation.
(05 Mar 2000)
open wound A wound in which the tissues are exposed to the air.
(05 Mar 2000)
fractures, open Fractures in which there is an external wound communicating with the break of the bone.
(12 Dec 1998)
Abbott's method A method of treatment of scoliosis by use of a series of plaster jackets applied after partial correction of the curvature by external force.
(05 Mar 2000)
Abell-Kendall method A standard method for estimation of total serum cholesterol involving saponification of cholesterol ester by hydroxide, extraction with petroleum ether, and colour development with acetic anhydride-sulfuric acid; the method avoids interference by bilirubin, protein, and haemoglobin.
(05 Mar 2000)
activated sludge method A method of sewage disposal in which the sewage is treated with 15% bacterially active, liquid sludge, which is produced by repeated vigorous aeration of fresh sewage to form floccules or sediment; when this flocculation process is complete, the resulting activated sludge contains large numbers of bacteria, together with yeasts, molds, and protozoa, which actively effect the oxidation of organic compounds; this mixture is piped to a sedimentation tank, the effluent from which is completely treated sewage.
(05 Mar 2000)
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