| ORS | olfactory reference syndrome; oral rehydration solution; oral surgery, oral surgeon; Orthopaedic Res... |
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| OT | objective test; oblique talus; occlusion time; occupational therapist, occupational therapy; ocular ... |
| OTU | olfactory tubercle; operational taxonomic unit |
| CR | calculation rate; calculus removed; calorie-restricted; cardiac rehabilitation; cardiac resuscitatio... |
| CRL | cell repository line; Certified Record Librarian; complement receptor location; complement receptor ... |
| olfactory peduncle | A nervelike, white band composed primarily of nerve fibres originating from the mitral cells and tufted cells of the olfactory bulb but also containing the scattered cells of the anterior olfactory nucleus. The tract is closely applied to the ventral surface of the frontal lobe, and attaches itself to the base of the cerebral hemisphere at the olfactory trigone, beyond which it extends in the form of the olfactory striae which distribute their fibres to the olfactory tubercle and, in largest number, to the olfactory cortex on and around the uncus of the parahippocampal gyrus. See: olfactory nerves. Synonym: tractus olfactorius, olfactory peduncle. (05 Mar 2000) |
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| olfactory pits | The paired depressions formed when the nasal placodes come to lie below the general external contour of the developing face as a result of the rapid growth of the adjacent nasal elevations; the pit's are the primordia of the rostral portions of the nasal chambers. Synonym: olfactory pits. (05 Mar 2000) |
| olfactory placodes | Paired ectodermal placode's which come to lie in the bottom of the olfactory pits as the pits are deepened by the growth of the surrounding medial and lateral nasal processes. Synonym: nasal placodes. (05 Mar 2000) |
| olfactory pyramid | A small area of gray matter situated between the roots of the olfactory tracts; it is continuous caudally with the anterior perforated substance. (05 Mar 2000) |
| olfactory region of tunica mucosa of nose | The specialised olfactory receptive area that includes the upper one-third of the nasal septum and the lateral wall above the superior concha; it is lined with olfactory mucosa. Synonym: regio olfactoria tunicae mucosae nasi, olfactory region of tunica mucosa of nose, Schultze's membrane. (05 Mar 2000) |
| olfactory roots | Three distinct fibre bands (stria medialis, stria intermedia, stria lateralis) that caudally extend the olfactory tract beyond its attachment to the olfactory trigone. The medial stria curves dorsally into the tenia tecta; the intermediate, often barely visible, extends straight back and terminates in the olfactory tubercle; the lateral olfactory stria, the largest of the three, passes along the lateral side of the olfactory tubercle, curving laterally as far as the limen insulae, then sharply medially to reach the uncus of the parahippocampal gyrus where it terminates in the plexiform layer of the olfactory cortex. See: medial longitudinal stria. Synonym: striae olfactoriae, olfactory roots. (05 Mar 2000) |
| olfactory striae | Three distinct fibre bands (stria medialis, stria intermedia, stria lateralis) that caudally extend the olfactory tract beyond its attachment to the olfactory trigone. The medial stria curves dorsally into the tenia tecta; the intermediate, often barely visible, extends straight back and terminates in the olfactory tubercle; the lateral olfactory stria, the largest of the three, passes along the lateral side of the olfactory tubercle, curving laterally as far as the limen insulae, then sharply medially to reach the uncus of the parahippocampal gyrus where it terminates in the plexiform layer of the olfactory cortex. See: medial longitudinal stria. Synonym: striae olfactoriae, olfactory roots. (05 Mar 2000) |
| olfactory sulcus | The sagittal sulcus on the inferior or orbital surface of each frontal lobe of the cerebrum, demarcating the straight gyrus from the orbital gyri, and covered on the orbital surface by the olfactory bulb and tract. Synonym: sulcus olfactorius, olfactory groove. (05 Mar 2000) |
| olfactory sulcus of nasal cavity | The narrow groove in the nasal cavity above the agger nasi that leads from the atrium to the olfactory area. Synonym: sulcus olfactorius cavum nasi. (05 Mar 2000) |
| olfactory tract | A nervelike, white band composed primarily of nerve fibres originating from the mitral cells and tufted cells of the olfactory bulb but also containing the scattered cells of the anterior olfactory nucleus. The tract is closely applied to the ventral surface of the frontal lobe, and attaches itself to the base of the cerebral hemisphere at the olfactory trigone, beyond which it extends in the form of the olfactory striae which distribute their fibres to the olfactory tubercle and, in largest number, to the olfactory cortex on and around the uncus of the parahippocampal gyrus. See: olfactory nerves. Synonym: tractus olfactorius, olfactory peduncle. (05 Mar 2000) |
| olfactory trigone | A grayish triangular area corresponding to the attachment of the olfactory peduncle ("olfactory nerve" or olfactory tract) to the base of the brain, at the anterior border of the anterior perforated substance. Synonym: trigonum olfactorium. (05 Mar 2000) |
| olfactory tubercle | A small, oval area at the base of the cerebral hemisphere, between the diverging medial and lateral olfactory striae, in the anteromedial part of the anterior perforated substance; it is formed by a small area of allocortex characterised by the presence of the islands of Calleja. Corresponding to a much more prominent structure in nonprimate mammals (especially rodents and insectivores), the olfactory tubercle receives fibres from the olfactory bulb by way of the intermediate olfactory stria; it has efferent connections with the hypothalamus and the mediodorsal nucleus of the thalamus. Synonym: tuberculum olfactorium. (05 Mar 2000) |
| acetylcholine receptor antibodies | <neurology, investigation> A test used to measure the amount of antibodies to acetylcholine receptors on nerve endings. This is a diagnostic test for myasthenia gravis. A normal value is no antibodies in the bloodstream. Acetylcholine receptor (AChR) binding autoantibodies (i.e. Antibodies reactive with several epitopes other than the binding site for acetylcholine or alpha-bungarotoxin) are present in approximately 88% of patients with generalised myasthenia gravis, 70% of ocular myasthenia and in approximately 80% of myasthenia gravis in remission. Although serum concentrations of AChR binding autoantibodies do not in general correlate well with severity of weakness, there is typical decrease in concentration as weakness improves with immunosuppressive therapy. AChR blocking autoantibodies (i.e., antibodies reactive with the AChR binding site) are present in about 50% of patients with myasthenia gravis, 30% with ocular myasthenia gravis and 20% of myasthenia gravis in remission, AChR blocking autoantibodies are the only AChR autoantibodies present in about 1% of myasthenia gravis. AChR modulating autoantibodies (i.e., autoantibodies which cross-link AChRs and cause their removal from muscle membrane surfaces) are present in more than 90% of myasthenia gravis and occasionally are the only AchR autoantibodies detectable in mild, recent onset or ocular-restricted myasthenia gravis. Results for AChR modulating autoantibodies can be transiently false-positive due to curare-like drugs used during general anesthesia. AChR autoantibodies of one or more types are found in at least 80% of ocular myasthenia gravis. Although generally absent in neurological conditions other than myasthenia gravis(and consequently unlikely to cause confusion in neurodiagnosis), false-positive results for AChR autoantibodies occasionally occur in primary biliary cirrhosis, tardive dyskinesia, autoimmune thyroiditis, the elderly, amyotrophic lateral sclerosis patients treated with cobra venom and patients with thymoma in the absence of myasthenia gravis. Approximately 1% of patients with rheumatoid arthritis treated with D-penicillamine develop AChR autoantibodies and myasthenia gravis, both of which disappear when the drug is discontinued. Babies born to ~10% of myasthenia gravis mothers have a transient neonatal form of myasthenia gravis that responds well to anticholinesterase therapy and usually remits within 1 month as maternal IgG disappears. (29 Dec 1997) |
| amino acid receptor | <biochemistry> Ligand gated ion channels with specific receptors for amino acid transmitters. An extended protein superfamily that also includes subunits of the nicotinic acetylcholine receptor. (18 Nov 1997) |
| AMPA receptor | <cell biology> Glutamate operated ion channel. See: excitatory amino acid receptor channels. (05 Feb 1998) |