| nodular tuberculid | A type of panniculitis characterised histologically by the presence of granulomas, vasculitis, and necrosis. It is traditionally considered to be the tuberculous counterpart of nodular vasculitis, but is now known to occur without tuberculous precedent. It is seen most commonly in adolescent and menopausal women, is initiated or exacerbated by cold weather, and typically presents as one or more recurrent erythrocyanotic nodules or plaques on the calves. The nodules may progress to form indurations, ulcerations, and scars. (12 Dec 1998) |
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| nodular vasculitis | Chronic or recurrent nodular lesions of subcutaneous tissue, especially of the legs of older women, with lobular panniculitis, granulomatous inflammation with multinucleated giant cells, focal necrosis, and obliterative inflammation of the small blood vessels, resembling erythema induratum but without evidence of associated tuberculosis. (05 Mar 2000) |
| toxic nodular goitre | <endocrinology> An enlarged thyroid gland which contains nodules which release excess thyroid hormone. This condition usually arises from long-standing simple goitre in the elderly. Symptoms of hyperthyroidism result. (12 Jan 1998) |
| focal nodular hyperplasia | <radiology> Focal nodules of normal hepatocytes, Kuppfer cells and bile ducts, F more than M, rare, benign, multiple in 20%, haemorrhage (most common complication) in only 2-3% (unlike hepatic adenoma), stellate fibrous septae (stellate scar), NM: normal or increased uptake on HIDA and sulfur colloid (12 Dec 1998) |
| localised nodular tenosynovitis | A nodule, possibly inflammatory in nature, arising commonly from the flexor sheath of the fingers and thumb; composed of fibrous tissue, lipid-and haemosiderin-containing macrophages, and multinucleated giant cells. Synonym: localised nodular tenosynovitis. (05 Mar 2000) |
| adult T-cell lymphoma | <tumour> An acute or subacute disease associated with a human T-cell virus, with lymphadenopathy, hepatosplenomegaly, skin lesions, peripheral blood involvement, and hypercalcaemia. Synonym: adult T-cell leukaemia. (05 Mar 2000) |
| anaplastic large cell lymphoma | <tumour> A form of lymphoma characterised by anaplasia of cells, sinusoidal growth, and immunoreactivity with CD30 (Ki-1 or Ber-H2). Synonym: Ki-1+ lymphoma. (05 Mar 2000) |
| benign lymphoma of the rectum | A rectal polyp composed of lymphoid tissue with follicle formation, covered by mucosa. (05 Mar 2000) |
| burkitt lymphoma | A form of undifferentiated malignant lymphoma usually found in central africa, but also reported in other parts of the world. It is commonly manifested as a large osteolytic lesion in the jaw or as an abdominal mass. B-cell antigens are expressed on the immature cells that make up the tumour in virtually all cases of burkitt lymphoma. The epstein-barr virus (herpes virus 4, human) has been isolated from burkitt lymphoma cases in africa and it is implicated as the causative agent in these cases; however, most non-african cases are ebv-negative. (12 Dec 1998) |
| Burkitt's lymphoma | <oncology, tumour> A type of Non-Hodgkin lymphoma that most often occurs in young people between the ages of 12 and 30. The disease usually causes a rapidly growing tumour in the abdomen. (12 May 1997) |
| cancer, lymphoma, hodgkin's | A type of lymphoma (cancer of the lymphatic system). The most common symptom of Hodgkin's disease is a painless swelling in the lymph nodes in the neck, underarm, or groin. Hodgkin's disease is diagnosed when abnormal tissue is detected by a pathologist after a biopsy of an enlarged lymph node. Treatment usually includes radiation therapy or chemotherapy. Regular follow-up examinations are important after treatment for Hodgkin's disease. Patients treated for Hodgkin's disease have an increased risk of developing other types of cancer later in life, especially leukaemia. (12 Dec 1998) |
| cancer, lymphoma, non-hodgkin's | A lymphoma is a cancer that develops in the lymphatic system. The most common symptom of non-Hodgkin's lymphomas is a painless swelling in the lymph nodes in the neck, underarm, or groin. Non-Hodgkin's lymphomas are diagnosed with a biopsy of an enlarged lymph node. Follow-up examinations are important after lymphoma treatment. Most relapses occur in the first 2 years after therapy. (12 Dec 1998) |
| canine malignant lymphoma | <tumour> A progressive fatal disease of dogs characterised by neoplastic transformation and proliferation of lymphoid cells, usually originating in solid lymphoid organs (lymphosarcoma) or bone marrow (lymphocytic leukaemia). (05 Mar 2000) |
| malignant lymphoma | <tumour> A general term for ordinarily malignant neoplasms of lymphoid and reticuloendothelial tissues which present as apparently circumscribed solid tumours composed of cells that appear primitive or resemble lymphocytes, plasma cells, or histiocytes. Lymphomas appear most frequently in lymph nodes, spleen, or other normal sites of lymphoreticular cells; when disseminated, Lymphoma's, especially of the lymphocytic type, may invade the peripheral blood and manifest as leukaemia. Lymphomas are classified by cell type, degrees of differentiation, and nodular or diffuse pattern; Hodgkin's disease and Burkitt's lymphoma are special forms. (05 Mar 2000) |
| Mediterranean lymphoma | A spectrum of conditions ranging from a benign plasma cell hyperplasia to a highly malignant lymphoma of the small intestine. (12 Dec 1998) |