| dark t2 lesion | <radiology> (short T2), acute haemorrhage (deoxyHb), haemosiderin, physiologic iron (basal ganglia, etc.), mucinous lesions (?) most abnormalities have long T1 and T2 (dark/bright). Compare: bright T1 lesion. (07 Mar 2000) |
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| supranuclear lesion | Injury to cerebral descending (corticonuclear) fibres above the brainstem or spinal motor nerve nucleus. Synonym: upper motor neuron lesion. (05 Mar 2000) |
| Dreulofoy's lesion | An abnormally large submucosal artery located in the proximal stomach that may be the site of acute and recurrent episodes of massive haemorrhage. (05 Mar 2000) |
| Duret's lesion | Small haemorrhage(s) in the floor of the fourth ventricle or beneath the aqueduct of Sylvius. (05 Mar 2000) |
| Janeway lesion | One of the stigmata of infectious endocarditis: irregular, erythematous, flat, painless macules on the palms, soles, thenar and hypothenar eminences of the hands, tips of the fingers, and plantar surfaces of the toes; rarely a diffuse rash. In acute endocarditis the lesions may be haemorrhagic or purple. (05 Mar 2000) |
| upper motor neuron lesion | Injury to cerebral descending (corticonuclear) fibres above the brainstem or spinal motor nerve nucleus. Synonym: upper motor neuron lesion. (05 Mar 2000) |
| Lennert's lesion | <tumour> Malignant lymphoma with a high proportion of diffusely scattered epithelioid cells, tonsillar involvement, and an unpredictable course. Synonym: Lennert's lesion. (05 Mar 2000) |
| lesion | <pathology> Any pathological or traumatic discontinuity of tissue or loss of function of a part. Origin: L. Laesio, laedere = to hurt (18 Nov 1997) |
| Lohlein-Baehr lesion | Focal embolic glomerulonephritis occurring in bacterial endocarditis. Synonym: Baehr-Lohlein lesion. (05 Mar 2000) |
| lower motor neuron lesion | Injury to motor cells in the brainstem or spinal cord, or of the axons derived from them. (05 Mar 2000) |
| aaa disease | Endemic anaemia of ancient Egypt, ascribed in the Papyrus Ebers to intestinal infestation with ancylostoma; now called ancylostomiasis. (05 Mar 2000) |
| ABO haemolytic disease of the newborn | Erythroblastosis foetalis due to maternal-foetal incompatibility with respect to an antigen of the ABO blood group; the foetus possesses A or B antigen which is lacking in the mother, and the mother produces immune antibody which causes haemolysis of foetal erythrocytes. (05 Mar 2000) |
| accumulation disease | A disease characterised by abnormal accumulation of a metabolic product in certain cells and tissues; examples include the mucopolysaccharidoses, lipoidoses. (05 Mar 2000) |
| Acosta's disease | A condition that results from prolonged exposure to high altitude. Symptoms include a continuous dry cough, shortness of breath, poor exercise tolerance, dizziness, headache, sleep difficulty, anorexia, confusion, fatigue and a rapid pulse. Treatment includes the immediate movement to a lower altitude. Prophylaxis has been accomplished successfully with the use of acetazolamide (Diamox). (27 Sep 1997) |
| acquired immunodeficiency disease | Acquired immunodeficiency disease: Disease caused by infection with the human immunodeficiency virus (HIV). (12 Dec 1998) |