| NFND | National Foundation for Neuromuscular Diseases |
|---|---|
| NM | near-miss; neomycin; neuromedin; neuromuscular; neutrophil migration; nictitating membrane; nitrogen... |
| NMBA | neuromuscular blocking agent |
| NMC | National Medical Care; Naval Medical Center; neuromuscular control; nonmotor condition; nucleus reti... |
| NMES | neuromuscular electrical stimulation |
| spindle fibre | <cell biology> Microtubules of the spindle that interdigitate at the equatorial plane with microtubules of the opposite polarity derived from the opposite pole microtubule organising centre. Usually distinguished from kinetochore fibres that are microtubules that link the poles with the kinetochore, although these could be included in a broader use of the term. (18 Nov 1997) |
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| spindle-shaped | 1. Having the shape of a spindle. 2. <botany> Thickest in the middle, and tapering to both ends; fusiform; applied chiefly to roots. Source: Websters Dictionary (01 Mar 1998) |
| spindle-shaped muscle | <anatomy> One that has a fleshy belly, tapering at either extremity. Synonym: musculus fusiformis, spindle-shaped muscle. (05 Mar 2000) |
| neurotendinous spindle | <cell biology, physiology> A proprioceptive sensory nerve ending embedded among the fibres of a tendon, often near the musculotendinous junction; it is compressed and activated by any increase of the tendon's tension, caused either by active contraction or passive stretch of the corresponding muscle. Synonym: neurotendinous organ, neurotendinous spindle. (05 Mar 2000) |
| nevus, epithelioid and spindle cell | A benign compound nevus occurring most often in children before puberty, composed of spindle and epithelioid cells located mainly in the dermis, sometimes in association with large atypical cells and multinucleate cells, and having a close histopathological resemblance to malignant melanoma. The tumour presents as a smooth to slightly scaly, round to oval, raised, firm papule or nodule, ranging in colour from pink-tan to purplish red, often with surface telangiectasia. (12 Dec 1998) |
| nevus, spindle cell | A form of pigmented nevus showing intense melanocytic activity around the dermo-epidermal junction. Large numbers of spindle-shaped melanocytes proliferate downward toward the dermis and usually a large amount of pigment is present. It was first described in 1976 and the bulk of patients reported have been young females with the lesions presenting on the thighs. (12 Dec 1998) |
| nuclear spindle | See: spindle and mitosis. (18 Nov 1997) |
| Krukenberg's spindle | A vertical fusiform area of melanin pigmentation on the posterior surface of the central cornea. (05 Mar 2000) |
| Kuhne's spindle | A fusiform end organ in skeletal muscle in which afferent and a few efferent nerve fibres terminate; it contains from 3 to 10 striated muscle fibres (intrafusal fibres) that are much smaller than the ordinary muscle fibres, are separated from them by a capsule that encloses the organ, and are innervated by the thin axon of a gamma motoneuron (gamma motor fibre); the sensory endings that occur on the intrafusal fibres are either annulospiral or flower spray endings; this sensory end organ is particularly sensitive to passive stretch of the muscle in which it is enclosed. Synonym: Kuhne's spindle, muscle spindle. (05 Mar 2000) |
| absolute terminal innervation ratio | The number of motor endplates divided by the number of terminal axons related to them. (05 Mar 2000) |
| amino-terminal | <biochemistry> The end of a protein or polypeptide chain with the unattached amino group or the aminoacyl residue containing it. Each amino acid in the chain has an amino group on one side, which is attached to the carboxyl group (COOH group) of the previous amino acid, and a carboxyl group on the other side (which is attached to the amino group of the next amino acid). The other end of the polypeptide chain is called the carboxyl terminal. Synonym: NH2-terminal. (14 Aug 2000) |
| amino-terminal residue | <biochemistry> The only amino acid residue in a polypeptide chain that has a free alpha-amino group, it defines the amino terminus of the polypeptide. (09 Oct 1997) |
| axonal terminal boutons | The somewhat enlarged, often club-shaped endings by which axons make synaptic contacts with other nerve cells or with effector cells (muscle or gland cells). As isolated, by homogenizing brain or spinal cord, they contain acetylcholine and the related enzymes. Terminals contain neurotransmitters of various kinds, sometimes more than one. These can be demonstrated by chemical analysis and immunocytochemical methods. See: synapse. Synonym: axonal terminal boutons, end-feet, neuropodia, pieds terminaux, synaptic boutons, synaptic endings, synaptic terminals, terminal boutons, bouton terminaux. (05 Mar 2000) |
| carboxyl terminal | The end of a polypeptide chain with the unattached carboxyl group (a -COOH group). Each amino acid in the middle of the chain has an amino group (a -NH2 group) on one side (which is attached to the carboxyl group of the previous amino acid) and a carboxyl group on the other side (which is attached to the amino group of the next amino acid). The other end of the polypeptide chain is called the amino terminal. (09 Oct 1997) |
| carboxyl-terminal residue | This amino acid residue defines the carboxylterminus of the polypeptide, its the only residue with a free alpha-carboxyl group. (09 Oct 1997) |