| AITP | autoimmune idiopathic thrombocytopenic purpura |
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| ATP | adenosine triphosphate; ambient temperature and pressure; autoimmune thrombocytopenic purpura |
| CPP | cancer proneness phenotype; canine pancreatic polypeptide; cerebral perfusion pressure; chest pain p... |
| HGP | hepatic glucose production; hyperglobulinemic purpura |
| HPW | hypergammaglobulinemic purpura of Waldenstrom |
| purpura, schoenlein-henoch | A form of nonthrombocytopenic purpura due to a hypersensitivity vasculitis (vasculitis, hypersensitivity) associated with a variety of clinical symptoms including urticaria and erythema, arthropathy and arthritis, gastrointestinal symptoms, and renal involvement. (12 Dec 1998) |
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| purpura senilis | The occurrence of petechiae and ecchymoses on the atrophic skin of the legs in aged and debilitated subjects. (05 Mar 2000) |
| purpura simplex | The eruption of petechiae or larger ecchymoses, usually unaccompanied by constitutional symptoms and not associated with systemic illness. Synonym: nonthrombocytopenic purpura. (05 Mar 2000) |
| purpura symptomatica | A petechial eruption in scarlet fever and other exanthemas. (05 Mar 2000) |
| purpura, thrombocytopenic | Any form of purpura in which the platelet count is decreased. Many forms are thought to be caused by immunological mechanisms. (12 Dec 1998) |
| purpura, thrombocytopenic, idiopathic | Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IgG autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms. (12 Dec 1998) |
| purpura, thrombotic thrombocytopenic | A disease characterised by thrombocytopenia, haemolytic anaemia, bizarre neurological manifestations, azotemia, fever, and thromboses in terminal arterioles and capillaries. (12 Dec 1998) |
| purpura urticans | Purpura simplex accompanied by an urticarial eruption. (05 Mar 2000) |
| hyperglobulinaemic purpura | <haematology> A condition characterised by proliferation of cells resembling lymphocytes or plasma cells in the bone marrow, anaemia, increased sedimentation rate and hyperglobulinaemia. Physical findings include mucosal bleeding, skin purpura and enlargement of the lymph nodes, liver and spleen. Origin: Gr. Haima = blood (27 Sep 1997) |
| hyperglobulinemic purpura | A condition characterised by proliferation of cells resembling lymphocytes or plasma cells in the bone marrow, anaemia, increased sedimentation rate and hyperglobulinaemia. Physical findings include mucosal bleeding, skin purpura and enlargement of the lymph nodes, liver and spleen. (27 Sep 1997) |
| nonthrombocytopenic purpura | The eruption of petechiae or larger ecchymoses, usually unaccompanied by constitutional symptoms and not associated with systemic illness. Synonym: nonthrombocytopenic purpura. (05 Mar 2000) |
| idiopathic thrombocytopenia purpura | <haematology> A rare autoimmune disorder characterised by an acute shortage of platelets with resultant bruising and spontaneous bleeding. The platelet count becomes exceedingly low and spontaneous bleeding from the gums, gastrointestinal tract and nose can be seen. Physical examination may demonstrate enlargement of the spleen. A typical rash occurs to do microscopic haemorrhage of small blood vessels in the skin. Platelet counts under 10,000 can lead to spontaneous haemorrhage into the brain causing death. Treatment with corticosteroids is generally effective. Surgical removal of the spleen (splenectomy) is reserved for some patients. Anti-platelet antibodies are detectable in some cases. It may present in either an acute or a chronic form. Acronym: ITP (20 Sep 2002) |
| idiopathic thrombocytopenic purpura | <haematology> A rare autoimmune disorder characterised by an acute shortage of platelets with resultant bruising and spontaneous bleeding. The platelet count becomes exceedingly low and spontaneous bleeding from the gums, gastrointestinal tract and nose can be seen. Physical examination may demonstrate enlargement of the spleen. A typical rash occurs to do microscopic haemorrhage of small blood vessels in the skin. Platelet counts under 10,000 can lead to spontaneous haemorrhage into the brain causing death. Treatment with corticosteroids is generally effective. Surgical removal of the spleen (splenectomy) is reserved for some patients. Anti-platelet antibodies are detectable in some cases. It may present in either an acute or a chronic form. Acronym: ITP (20 Sep 2002) |
| immune thrombocytopenic purpura | <haematology> A low number of platelets in the blood, which is common in people with HIV, but often resolves as immune deficiency worsens. HIV-related ITP usually does not have serious consequences. Its cause has not been definitely determined. Treatment with AZT frequently alleviates the condition. (09 Oct 1997) |
| thrombocytopenia purpura | <haematology> In severe thrombocytopenia, bleeding into skin leads to small petechial haemorrhages. Primary thrombocytopenia purpura is of unknown cause but results from an autoimmune mechanism that causes platelet destruction. Secondary thrombocytopenic purpura may result from drug-induced type II hypersensitivity in which platelets coated with antibody to the drug (which is acting as a hapten) are destroyed in a complement mediated reaction. It can also follow a viral upper respiratory infection and may be seen in association with lupus. (15 Oct 1997) |