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myelinoclasis Destruction of myelin.
See: demyelination, dysmyelination.
Origin: myelin + G. Klasis, a breaking
(05 Mar 2000)
myelinogenesis Synonym: myelination.
Origin: myelin + G. Genesis, production
(05 Mar 2000)
myelinolysis Dissolution of the myelin sheaths of nerve fibres.
Origin: myelin + G. Lysis, dissolution
(05 Mar 2000)
myelinolysis, central pontine A form of massive demyelination of the pons occurring in malnutrition and alcoholism. The remarkable unsystematic dissolution of the sheaths of medullated fibres is its most certain feature. The lesion varies from only a few millimeters in diameter to almost the entire pons. The basic pathology is the destruction of the medullated sheaths throughout the lesions with relative sparing of the axis cylinders and intactness of the nerve cells of the pontine nuclei. Pathologically it is easily differentiated from infarction and the inflammatory demyelinations of multiple sclerosis and postinfectious encephalomyelitis. There does not appear to be a genetic, sex, or age factor. It is often, however, associated with some other serious disease, particularly chronic alcoholism. (adams & victor, principles of neurology, 2d ed, p720)
(12 Dec 1998)
myelinopathy A disorder affecting the myelin of peripheral nerve fibres, in contrast to one affecting axons (axonopathy).
(05 Mar 2000)
myelitic Relating to or affected by myelitis.
(05 Mar 2000)
myelitis <pathology> An infection of the bone marrow.
An inflammation or infectionof the spinal cord.
(09 Oct 1997)
myelitis, transverse Myelitis in which the functional effect of the lesions spans the width of the entire cord at a given level.
(12 Dec 1998)
myelo- 1. The bone marrow.
2. The spinal cord and medulla oblongata.
Compare: medullo-.
3. The myelin sheath of nerve fibres.
Origin: G. Myelos, medulla, marrow
(05 Mar 2000)
myeloablative agonists Agents that destroy bone marrow activity. They are used to prepare patients for bone marrow or stem cell transplantation.
(12 Dec 1998)
myeloarchitectonics The pattern of myelinated nerve fibres in the brain, as distinguished from cytoarchitectonics.
(05 Mar 2000)
myeloblast <haematology> An immature cell produced by and found in bone marrow which gives rise to granular leukocytes.
(09 Oct 1997)
myeloblastemia The presence of myeloblasts in the circulating blood.
Origin: myeloblast + G. Haima, blood
(05 Mar 2000)
myeloblastic <haematology> Immature cells of the myeloid series.
(13 Nov 1997)
myeloblastic leukaemia A form of granulocytic leukaemia in which there are large numbers of myeloblasts in various tissues (and organs) and in the circulating blood; the immature forms may amount to 30 to 60% (or even a greater proportion) of the increased total number of white blood cells. Used synonymously for acute granulocytic leukaemia.
Synonym: leukaemic myelosis.
(05 Mar 2000)
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