| down promoter mutation | <molecular biology> A mutation (a change in base pair sequence) in a promoter region, this results in lower gene expression (less transcription of the gene occurs). (09 Oct 1997) |
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| induced mutation | A mutation caused by exposure to a mutagen. (05 Mar 2000) |
| insertion mutation | A mutation caused by the insertion of at least one extra nucleotide basein a DNA sequence. (09 Oct 1997) |
| ochre mutation | Mutation that changes any codon to the termination codon UAA. (18 Nov 1997) |
| opal mutation | <molecular biology> Mutation that changes any codon to the termination codon UGA. (18 Nov 1997) |
| temperature sensitive mutation | <genetics, molecular biology> A type of conditional mutation in organism, somatic cell or virus that makes it possible to study genes whose total inactivation would be lethal. Such ts mutations can also make possible studies of the effect of reversible switching by temperature changes) in expression of the mutated gene. The usual mechanism of temperature sensitivity is that the mutated gene codes for a protein with a temperature dependent conformational instability, so that it possesses normal activity at one temperature (the permissive temperature), but is inactive at a second (nonpermissive) temperature. (18 Nov 1997) |
| transition mutation | A point mutation involving substitution of one base-pair for another, i.e., replacement of one purine for another and of one pyrimidine for another pyrimidine without change in the purine-pyrimidine orientation. (05 Mar 2000) |
| transversion mutation | A point mutation involving base substitution in which the orientation of purine and pyrimidine is reversed, in contradistinction to transition mutation. (05 Mar 2000) |
| umber mutation | A mutation yielding the termination codon UGA, resulting in premature termination of a polypeptide chain. Compare: suppressor mutation. Synonym: opal mutation. (05 Mar 2000) |
| unstable mutation | <molecular biology> A mutation that has a high likelihood of reverting to its original form. (13 Nov 1997) |
| up mutation | <molecular biology> Refers to any mutation in the promoter region of a gene which can trigger transcription initiation. (09 Oct 1997) |
| up promoter mutation | A mutation that increases the frequency of initiation of transcription. (05 Mar 2000) |
| forward mutation | Any mutation which renders a formerly functional gene nonfunctional. Compare: back mutation. (09 Oct 1997) |
| frameshift mutation | <molecular biology> A type of mutation that results from insertion or deletion of a single nucleotide into, or from, an open reading frame in the normal DNA sequence. Normally, the genetic code is read in the wrong frame, three nucleotides at a time, and the entire sequence downstream of the mutation, is translated into a polypeptide with a garbled amino acid sequence from the mutated codon onwards. These mutations may be induced by certain types of mutagens or may occur spontaneously and usually result in the generation, downstream, of nonsense, chain termination codons. Synonym: addition mutation, addition-deletion mutation, deletion mutation, reading-frameshift mutation. (21 Jun 2000) |
| lethal mutation | <genetics, molecular biology> Mutation that eventually results in the death of an organism carrying the mutation. (18 Nov 1997) |
| mutation |
Any heritable change in genetic material. This may be a chemical transformation of an individual gene (a gene or point mutation), which alters its function. On the other hand, this change may involve a rearrangement, or a gain or loss of part of a chromosome, which may be microscopically visible. This is designated a chromosomal mutation. Most mutations are harmful.
출처: www.bio.hw.ac.uk/edintox/glossall.htm
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| mutation rate |
The average occurrence of mutations in a species per a given unit of time.
출처: www.emc.maricopa.edu/faculty/farabee/BIOBK/BioBook...
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| mutation |
An alteration in a gene that results from a change to a part of the stretch of DNA that represents a gene. A
출처: cll.ucsd.edu/glossarym.htm
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| mutation |
A change in a DNA sequence.
출처: www.nigms.nih.gov/news/science_ed/genetics/glossar...
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| mutation |
A permanent change, a structural alteration, in the DNA or RNA. Mutations can be caused by many factors including environmental insults such as radiation and mutagenic chemicals. Mutations are sometimes attributed to random chance events.
출처: www.als.net/als101/glossary.asp
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