| large-hearted | Having a large or generous heart or disposition; noble; liberal. Large"-heartedness. Source: Websters Dictionary (01 Mar 1998) |
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| large interarch distance | A large distance between the maxillary and mandibular arches; may also imply an excessive vertical dimension. Synonym: open bite. (05 Mar 2000) |
| large muscle of helix | <anatomy> A narrow band of muscular fibres on the anterior border of the helix of the auricle arising from the spine and inserted at the point where the helix becomes transverse. Synonym: musculus helicis major, large muscle of helix. (05 Mar 2000) |
| large pelvis | The expanded portion of the pelvis above the brim. Synonym: pelvis major, false pelvis, large pelvis, pelvis spuria. (05 Mar 2000) |
| large pleural effusion | <radiology> 3 T's, tumour, TB, trauma (12 Dec 1998) |
| large pudendal lip | One of two rounded folds of integument forming the lateral boundaries of the pudendal cleft. The labia majora are the female homolog of the scrotum. Synonym: labium majus pudendi, large pudendal lip. (05 Mar 2000) |
| large saphenous vein | <anatomy, vein> Formed by the union of the dorsal vein of the great toe and the dorsal venous arch of the foot, ascends in front of the medial malleolus, behind the medial condyle of the femur, and traverses the saphenois hiatus in the fascia lata to empty into the femoral vein in the upper part of the femoral triangle. Synonym: vena saphena magna, large saphenous vein, long saphenous vein. (05 Mar 2000) |
| large uterus | <radiology> Multiparity, pregnancy, molar pregnancy, neoplasm (12 Dec 1998) |
| large vein | <anatomy, vein> A vein, such as the inferior vena cava, characterised by having a reduced or absent tunica media and an adventitia with large bundles of longitudinally disposed smooth muscle. (05 Mar 2000) |
| large woody debris | Dead woody material greater than 20" in diameter on the ground or in a stream or river. It may consist of logs, trees, or parts of trees. Large woody debris contributes to long-term site productivity and health in several ways. It supplies nutrients to the soil, supports symbiotic fungi that are beneficial to conifers, and provides habitat for beneficial rodents and insects. (05 Dec 1998) |
| lymphoma, large-cell | A form of malignant lymphoma in which the malignant cells resemble histiocytes morphologically but are presently considered to be derived from lymphoid elements. These cells are irregular in shape with relatively abundant, frequently acidophilic cytoplasm. Large-cell lymphoma can occur in both nodular (follicular) and diffuse forms, with the latter being more frequently seen. (12 Dec 1998) |
| lymphoma, large-cell, diffuse | Malignant lymphoma composed of large cells which may be both cleaved and noncleaved. The pattern is predominantly diffuse. most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation. (12 Dec 1998) |
| lymphoma, large-cell, follicular | Malignant lymphoma in which the majority of neoplastic cells within the follicles are large cleaved or noncleaved cells. The degree to which the follicular centre cells retain their ability to form follicles varies with the state of B-cell transformation. (12 Dec 1998) |
| lymphoma, large-cell, immunoblastic | Malignant lymphoma characterised by the presence of immunoblasts with uniformly round-to-oval nuclei, one or more prominent nucleoli, and abundant cytoplasm. This class may be subdivided into plasmacytoid and clear-cell types based on cytoplasmic characteristics. A third category, pleomorphous, may be analogous to some of the peripheral T-cell lymphomas (lymphoma, T-cell, peripheral) recorded in both the united states and japan. (12 Dec 1998) |
| lymphoma, large-cell, ki-1 | A large-cell, non-hodgkin's, malignant lymphoma with pleomorphic appearance and reactivity with the monoclonal antibody ki-1. The lymphoma is most often found in the skin and lymph nodes and expresses the ki-1 (CD30) antigen (antigens, CD30) on its surface. It is often mistaken for metastatic carcinoma and malignant histiocytosis. (12 Dec 1998) |