| MEV | maximum exercise ventilation; mevalonate; minimal excursionary ventilation; murine erythroblastosis ... |
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| MLVAR | amphotropic receptor for murine leukemia virus |
| MMLV | Moloney murine leukemia virus |
| MMuLV | Moloney murine leukemia virus |
| Mo-MLV | Moloney murine leukemia virus |
| murine hepatitis | A form of hepatitis in mice due to synergism between the mouse hepatitis virus and Eperythrozoon coccoides. Synonym: murine hepatitis. (05 Mar 2000) |
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| murine leprosy | A slowly but progressively fatal form of leprosy occurring in rats, caused by Mycobacterium lepraemurium; it appears in two forms, glandular and musculocutaneous; causes induration, alopecia, and eventually ulceration. Synonym: mouse leprosy, murine leprosy. (05 Mar 2000) |
| murine typhus | An acute infectious disease with fever, headache, and rash, all quite similar to, but milder than, epidemic typhus, caused by a related microoganism, rickettsia typhi (mooseri), transmitted to humans by rat fleas (xenopsylla cheopis). The animal reservoir includes rats, mice and other rodents. Murine typhus occurs sporadically worldwide but is more prevalent in congested rat-infested urban areas. Also known as endemic typhus, rat-flea typhus; urban typhus of malaya). (12 Dec 1998) |
| sarcoma viruses, murine | Species of replication-defective mammalian type c retroviruses (retroviruses type c, mammalian) which are capable of transforming cells, but which replicate and produce tumours only in the presence of murine leukaemia viruses (leukaemia viruses, murine). (12 Dec 1998) |
| transmissible murine colonic hyperplasia | A disease of young mice caused by the bacterium Citrobacter freundii and characterised by diarrhoea and mucosal hyperplasia of the descending colon. (05 Mar 2000) |
| tumour viruses, murine | Species of mammalian type c retroviruses (retroviruses type c, mammalian) that cause solid tumours or leukaemias in mice. (12 Dec 1998) |
| typhus, murine | An acute infectious disease with fever, headache, and rash, all quite similar to, but milder than, epidemic typhus, caused by a related microoganism, rickettsia typhi (mooseri), transmitted to humans by rat fleas (xenopsylla cheopis). The animal reservoir includes rats, mice and other rodents. Murine typhus occurs sporadically worldwide but is more prevalent in congested rat-infested urban areas. Also known as endemic typhus, rat-flea typhus, and urban typhus of malaya. (12 Dec 1998) |
| Friend murine erythroleukaemia cell | <cell culture> Lines of mouse erythroblasts transformed by the Friend virus, that can be induced to differentiate terminally, producing haemoglobin, by various agents such as dimethyl sulphoxide. (18 Nov 1997) |
| bovine virus diarrhoea virus | A virus of the genus Pestivirus, in the family Togaviridae, causing bovine virus diarrhoea; New York, Oregon, and Indiana strains of the virus are recognised. Synonym: mucosal disease virus. (05 Mar 2000) |
| accelerated phase of leukaemia | Refers to chronic myelogenous leukaemia that is progressing. The number of immature, abnormal white blood cells in the bone marrow and blood is higher than in the chronic phase, but not as high as in the blast phase. (12 Dec 1998) |
| acute granulocytic leukaemia | <haematology> A form of leukaemia which is characterised by the proliferation of immature white blood cells (granulocytes) in the bloodstream. Occurs primarily in adults and in infants under 1 year of age. Complications include abnormal bleeding and susceptibility to infections. Symptoms include fatigue, weight loss, fevers, weakness, pallor, bone pains, bleeding gums, nosebleeds, easy bruising, enlarged lymph nodes and joint pains. Treatment includes chemotherapy and/or bone marrow transplant. Origin: Gr. Haima = blood (27 Sep 1997) |
| acute leukaemia | <haematology> A rapidly progressive cancer of the blood of sudden onset and characterised by the uncontrolled proliferation of immature blood cells which take over the bone marrow and spill into the blood stream. If left untreated is fatal within a few weeks or months. See: acute lymphoblastic leukaemia, acute myeloid leukaemia. Origin: Gr. Haima = blood (11 Nov 1997) |
| acute lymphoblastic leukaemia | <haematology> A rapidly progressing cancer of the blood affecting the type of white blood cell known as lymphocytes. Approximately 650 new cases are diagnosed every year in the UK and it is the most common form of childhood leukaemia. Acronym: ALL Origin: Gr. Haima = blood (11 Nov 1997) |
| acute lymphocytic leukaemia | <radiology> 95% of cases of leukaemia in children, bone changes in 50-70% of kids (vs. 10% in adults); seen as early as 1 month after onset of symptoms, wrists and knees most commonly affected, bony defects: metaphyseal radiolucent bands! (similar findings in scurvy, JRA, syphilis), osteolytic lesions, periosteal reaction, osteosclerosis (12 Dec 1998) |
| acute monocytic leukaemia | <haematology> The most common translocation in this disorder of poorly differentiated monocytic cells involves chromosome region 11q in a large percentage of cases. The translocation involves a cellular oncogene, c-ets which is mapped to the 11q23-24 region. The most common translocations reported are t(6;11), t(9;11), t(11;17) and t(11;19), of which t(9;11) (p21-22;q23) is by far the most frequently detected and implicated in acute myeloid leukaemia. The cells express CD14 surface antigen, which is diagnostic of monocytic cells. Acronym: AML Classification: FAB M5 (07 Apr 1998) |