| toxic nodular goitre | <endocrinology> An enlarged thyroid gland which contains nodules which release excess thyroid hormone. This condition usually arises from long-standing simple goitre in the elderly. Symptoms of hyperthyroidism result. (12 Jan 1998) |
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| focal nodular hyperplasia | <radiology> Focal nodules of normal hepatocytes, Kuppfer cells and bile ducts, F more than M, rare, benign, multiple in 20%, haemorrhage (most common complication) in only 2-3% (unlike hepatic adenoma), stellate fibrous septae (stellate scar), NM: normal or increased uptake on HIDA and sulfur colloid (12 Dec 1998) |
| localised nodular tenosynovitis | A nodule, possibly inflammatory in nature, arising commonly from the flexor sheath of the fingers and thumb; composed of fibrous tissue, lipid-and haemosiderin-containing macrophages, and multinucleated giant cells. Synonym: localised nodular tenosynovitis. (05 Mar 2000) |
| aberrant goiter | Enlargement of a supernumerary thyroid gland. Synonym: struma aberrata. (05 Mar 2000) |
| acute goiter | A goiter that develops very rapidly. (05 Mar 2000) |
| adenomatous goiter | An enlargement of the thyroid gland due to the growth of one or more encapsulated adenomas or multiple nonencapsulated colloid nodules within its substance. (05 Mar 2000) |
| Basedow's goiter | Colloid goiter which becomes hyperfunctional after the ingestion of excess iodine, the Jod-Basedow phenomenon. (05 Mar 2000) |
| cabbage goiter | Goiter due to ingestion of cabbage or other goitrogenic foodstuff. (05 Mar 2000) |
| parenchymatous goiter | A form of goiter in which there is a great increase in the follicles with proliferation of the epithelium. Synonym: follicular goiter. (05 Mar 2000) |
| goiter | Enlargement of the thyroid gland. A goiter is not cancerous. A goiter can be associated with normal, elevated (hyperthyroidism) or decreased (hypothyroidism) thyroid hormone levels in the blood. (12 Dec 1998) |
| goiter, diffuse toxic | Graves' disease, the most common cause of hyperthroidism, too much thyroid hormone. (12 Dec 1998) |
| goiter, endemic | Enlargement of the thyroid gland in a significantly large fraction of a population group, generally considered to be due to insufficient iodine in the diet. (12 Dec 1998) |
| goiter, iodide | Just as too little iodine can cause thyroid disease, so may prolonged intake of too much iodine also lead to the development of goiter (swelling of the thyroid gland) and hypothyroidism (abnormally low thyroid activity). Certain foods and medications contain large amounts of iodine. Examples include seaweed; iodine-rich expectorants (such as SSKI and Lugol's solution) used in the treatment of cough, asthma, chronic pulmonary disease; and amiodarone (Cardorone), an iodine-rich medication used in the control of abnormal heart rhythms (cardiac arrhythmias). (12 Dec 1998) |
| goiter, substernal | An enlarged thyroid gland where the enlarged gland is situated beneath the sternum. (12 Dec 1998) |
| goiter, toxic multinodular | Condition in which the thyroid gland contains multiple lumps (nodules) that are overactive and produce excess thyroid hormones. This condition is also known as Parry's disease or Plummer's disease. (12 Dec 1998) |