| HPAC | high-performance anion-exchange chromatography; hypothalamo-pituitary-adreno-cortical |
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| HPLAC | high-pressure liquid-affinity chromatography |
| HRC | hereditary renal cancer; high-resolution chromatography; horse red cell; human rights committee |
| HSLC | high-speed liquid chromatography |
| IEC | injection electrode catheter; International Electrotechnical Commission; intraepithelial carcinoma; ... |
| ion exchange chromatography | <procedure> Separation of molecules by absorption and desorption from charged polymers. An important technique for protein purification. For small molecules the support is usually polystyrene, but for macromolecules, cellulose, acrylamide or agarose supports give less non-specific absorption and denaturation. Typical charged residues are CM carboxymethyl) or DEAE (diethylaminoethyl). (27 Oct 1998) |
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| thin layer chromatography | <technique> Chromatography using a thin layer of powdered medium on an inert sheet to support the stationary phase. Faster than paper chromatography, gives higher resolution and requires smaller samples. (18 Nov 1997) |
| thin-layer chromatography | Chromatography through a thin layer of cellulose or similar inert material supported on a glass or plastic plate. (05 Mar 2000) |
| two-dimensional chromatography | Paper chromatography in which a spot, located originally in one corner of a sheet, is developed in one direction along one side of the sheet, after which the sheet is rotated 90 |
| liquid-liquid chromatography | Chromatography in which both the moving phase and the stationary (or reverse-moving) phase are liquids, as in countercurrent distribution. (05 Mar 2000) |
| relative molecular mass | The sum of the atomic weight's of all the atoms constituting a molecule; the mass of a molecule relative to the mass of a standard atom, now 12C (taken as 12.000). Relative molecular mass (Mr) is the mass relative to the dalton and has no units. See: atomic weight. Synonym: molecular mass, molecular weight ratio, relative molecular mass. (05 Mar 2000) |
| gram-molecular weight | Molecular weight expressed in grams. Compare: mole. (05 Mar 2000) |
| cloning, molecular | The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells. (12 Dec 1998) |
| models, molecular | Models used experimentally or theoretically to study molecular shape, electronic properties, or interactions; includes analogous molecules, computer-generated graphics, and mechanical structures. (12 Dec 1998) |
| molecular | <chemistry> Of, pertaining to or composed of molecules: a very small mass of matter. (18 Nov 1997) |
| molecular behaviour | <psychology> Behaviour described in small response units rather than larger ones; a specific response. Compare: molar behaviour. (05 Mar 2000) |
| molecular biology | <study> The study of the biochemistry of cells, it is closely linked to cell biology, in particular the biochemistry of DNA and cogeners. (16 Dec 1997) |
| molecular biophysics | Biophysics concerned with membrane processes, conformational and configurational properties of macromolecules, bioelectrical phenomena, etc. (05 Mar 2000) |
| molecular chaperones | A family of cellular proteins that mediate the correct assembly or disassembly of other polypeptides, and in some cases their assembly into oligomeric structures, but which are not components of those final structures. It is believed that chaperone proteins assist polypeptides to self-assemble by inhibiting alternative assembly pathways that produce nonfunctional structures. Some classes of molecular chaperones are the nucleoplasmins, the chaperonins, the heat-shock proteins 70, and the heat-shock proteins 90. (12 Dec 1998) |
| molecular clock | This term has two separate uses. 1. <molecular biology> The rate of fixation of mutations in DNA and thus times the rate of genetic diversification. 2. <cell biology> A biological system capable of maintaining up a timing rhythm or pulse. All such clocks are thought to be entrained by a natural oscillator such as the diurnal rhythm. (18 Nov 1997) |