| steroid 17 alpha-monooxygenase | <enzyme> A steroid hydroxylase system found in the microsomal membrane of the steroid-hormone producing tissues. It catalyses the 17-hydroxylation of steroids, such as progesterone or pregnenolone in the presence of NADPH and molecular oxygen. This is an important step in the biosynthesis of steroid hormones. Chemical name: Steroid, hydrogen-donor:oxygen oxidoreductase (17 alpha-hydroxylating) Registry number: EC 1.14.99.9 (12 Dec 1998) |
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| steroid 21-monooxygenase | <enzyme> A steroid hydroxylase system found in adrenal cortex microsomes. It catalyses the 21-hydroxylation of corticosteroids and shows a requirement for NADPH and molecular oxygen. Its deficiency is a cause of adrenogenital syndrome. Chemical name: Steroid,hydrogen-donor:oxygen oxidoreductase (21-hydroxylating) Registry number: EC 1.14.99.10 (12 Dec 1998) |
| steroid 9 alpha monooxygenase | <enzyme> Consists of an electron transport chain of NADH-dependent flavoprotein reductase and 2 iron-sulfur proteins; from nocardia Registry number: EC 1.14.99.- Synonym: steroid 9 alpha-hydroxylase (26 Jun 1999) |
| nitrilotriacetate monooxygenase | <enzyme> Two component monooxygenase; catalyses nitrilotriacetate and NADH to iminodiacetate and glyoxylate and nad in the presence of h and oxygen Registry number: EC 1.14.13.- Synonym: nta monooxygenase (26 Jun 1999) |
| nitrilotriacetic acid monooxygenase | <enzyme> Nadh and o2 required, forms ininodiacetic acid and glyoxylate Registry number: EC 1.7.- (26 Jun 1999) |
| diethylstilbestrol monooxygenase | <enzyme> Catalyses the hydroxylation of des to form 1-hydroxy-des Registry number: EC 1.13.99.- Synonym: des monooxygenase (26 Jun 1999) |
| dihydrofolate monooxygenase | <enzyme> 7,8-dihydrofolate plus 1/2 o2 gives 7,8-dihydropterin-6-aldehyde plus p-aminobenzoylglutamate Registry number: EC 1.13.- (26 Jun 1999) |
| dopamine beta-monooxygenase | A copper-containing enzyme catalyzing oxidation of ascorbate and 3,4-dihydroxyphenylethylamine simultaneously by O2 to yield norepinephrine, dehydroascorbate, and water; a crucial step in catecholamine metabolism. Synonym: dopamine beta-hydroxylase. (05 Mar 2000) |
| quinaldic acid 4-monooxygenase | <enzyme> Catalyses conversion of quinaldic acid to kynurenic acid in presence of oxygen, iron(ii), and NADH; do not confuse with quinaldic acid 4-oxidoreductase Registry number: EC 1.14.13.- (26 Jun 1999) |
| tertiary amine monooxygenase | <enzyme> Requires NADPH and fad; can be separated from dimethylamine mono-oxygenase; oxidises a variety of tertiary alkylamines up to tributylamine Registry number: EC 1.14.99.- Synonym: trimethylamine mono-oxygenase (26 Jun 1999) |
| tetracenomycin F1 monooxygenase | <enzyme> Catalyses the oxidation of naphthacenone tcm f1 to the 5,12-naphthaquinone tcm d3 in the biosynthesis of tcm c in streptomyces glaucescens; requires only oxygen for enzymatic oxidation; inactivated by p-chloromercuribenzoic acid, n-ethylmaleimide and diethyl pyrocarbonate Registry number: EC 1.14.99.- Synonym: tcm f1 monooxygenase, tcmh protein (26 Jun 1999) |
| toluene-3-monooxygenase | <enzyme> Degrades benzene and related aromatic hydrocarbons in pseudomonas pickettii Registry number: EC 1.14.13.- (26 Jun 1999) |
| toluene-4-monooxygenase | <enzyme> Enzyme system contains 3 protein components; the reconstituted enzyme system catalyses the oxidation of toluene to p-cresol by an NADPH-dependent monooxygenation reaction in which one atom of molecular oxygen in incorporated into the hydroxyl group cresol Registry number: EC 1.14.13.- (26 Jun 1999) |
| toluene ortho-monooxygenase | <enzyme> Enzyme from pseudomonas sp. Strain js150 acts on both toluene and benzene; amino acid sequence has been determined; also hydroxylates cresol to 3-methylcatechol Registry number: EC 1.13.12.- Synonym: toluene 2-monooxygenase, toluene-benzene-2-monooxygenase (26 Jun 1999) |
| tryptophan 2-monooxygenase | <enzyme> Forms indole-3-acetamide Registry number: EC 1.13.12.3 (26 Jun 1999) |