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MeSH(Medical Subject Headings) ¸ÂÃã °Ë»ö (http://www.nlm.nih.gov) °á°ú : 5 ÆäÀÌÁö: 3
  • MAP Kinase Kinase Kinase 4 - »õâ A 180-kDa MAP kinase kinase kinase with specificity for MAP KINASE KINASE 4 and MAP KINASE KINASE 6.
    Synonyms : MAP3K4 Protein Kinase, MAPKKK4 Protein, MEK Kinase 4, MEKK4 Protein, MEKK4 Protein Kinase, Mitogen-Activated Protein Kinase Kinase Kinase 4, Kinase, MEKK4 Protein, Mitogen Activated Protein Kinase Kinase Kinase 4, Protein Kinase, MAP3K4
  • MAP Kinase Kinase Kinase 5 - »õâ A 150-kDa MAP kinase kinase kinase that may play a role in the induction of APOPTOSIS. It has specificity for MAP KINASE KINASE 3; MAP KINASE KINASE 4; and MAP KINASE KINASE 6.
    Synonyms : ASK1 Protein Kinase, Apoptosis Signal-Regulating Kinase 1, MAP3K5 Protein Kinase, MAPK Kinase Kinase 5, MAPKKK5, Mitogen-Activated Kinase Kinase Kinase Kinase 5, Apoptosis Signal Regulating Kinase 1, Mitogen Activated Kinase Kinase Kinase Kinase 5
  • MAP Kinase Kinase Kinases - »õâ Mitogen-activated protein kinase kinase kinases (MAPKKKs) are serine-threonine protein kinases that initiate protein kinase signaling cascades. They phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES; (MAPKKs) which in turn phosphorylate MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs).
    Synonyms : Kinases, MAP Kinase Kinase, MAP Kinase Kinase Kinase, MAP3 Kinases, Mitogen-Activated Protein Kinase Kinase Kinases, Kinase Kinases, MAPK-ERK, Kinases, MAP3, Kinases, MAPK-ERK Kinase, Kinases, MEK, MAPK ERK Kinase Kinases
  • MAP Kinase Signaling System - »õâ An intracellular signaling system involving the MAP kinase cascades (three-membered protein kinase cascades). Various upstream activators, which act in response to extracellular stimuli, trigger the cascades by activating the first member of a cascade, MAP KINASE KINASE KINASES; (MAPKKKs). Activated MAPKKKs phosphorylate MITOGEN-ACTIVATED PROTEIN KINASE KINASES which in turn phosphorylate the MITOGEN-ACTIVATED PROTEIN KINASES; (MAPKs). The MAPKs then act on various downstream targets to affect gene expression. In mammals, there are several distinct MAP kinase pathways including the ERK (extracellular signal-regulated kinase) pathway, the SAPK/JNK (stress-activated protein kinase/c-jun kinase) pathway, and the p38 kinase pathway. There is some sharing of components among the pathways depending on which stimulus originates activation of the cascade.
    Synonyms : MAP Kinase Modules, MAP Kinase Signaling Cascades, Cascade, MAP Kinase, Cascades, MAP Kinase, Kinase Cascade, MAP, Kinase Cascades, MAP, Kinase Module, MAP, Kinase Modules, MAP, MAP Kinase Cascades, MAP Kinase Module, Module, MAP Kinase, Modules, MAP Kinase
  • Maple Syrup Urine Disease - »õâ An autosomal recessive inherited disorder with multiple forms of phenotypic expression, caused by a defect in the oxidative decarboxylation of branched-chain amino acids (AMINO ACIDS, BRANCHED-CHAIN). These metabolites accumulate in body fluids and render a "maple syrup" odor. The disease is divided into classic, intermediate, intermittent, and thiamine responsive subtypes. The classic form presents in the first week of life with ketoacidosis, hypoglycemia, emesis, neonatal seizures, and hypertonia. The intermediate and intermittent forms present in childhood or later with acute episodes of ataxia and vomiting. (From Adams et al., Principles of Neurology, 6th ed, p936)
    Synonyms : Classic Maple Syrup Urine Disease, Classical Maple Syrup Urine Disease, Intermediate Maple Syrup Urine Disease, Intermittent Maple Syrup Urine Disease, MSUD (Maple Syrup Urine Disease), Maple Syrup Urine Disease, Classic, Maple Syrup Urine Disease, Classical
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MeSH(Medical Subject Headings) À¯»ç °Ë»ö (http://www.nlm.nih.gov) °á°ú : 0 ÆäÀÌÁö: 3
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