| DPLN | diffuse proliferative lupus nephritis |
|---|---|
| DRL | dorsal root, lumbar; drug-related lupus |
| LA | lactic acid; large amount; laser angioplasty; late abortion; late antigen; latex agglutination; left... |
| LAC | La Crosse [virus]; lactase; left atrial circumflex [artery]; left atrial contraction; linguoaxiocerv... |
| LE | lactate extraction; left ear; left eye; leukocyte elastase; leukoerythrogenic; live embryo; Long Eva... |
| SCLE | Subacute Cutaneous Lupus Erythematosus |
|---|---|
| SLAM | Systemic Lupus Activity Measure |
| SLE | Systemic Lupus Erytematosus |
| SLEDAI | Systemic Lupus Erythematosus Disease Activity Index |
| SLICC/ACR | Systemic Lupus International Collaborating Clinics/American College of Rheumatology |
| lupus erythematosus cell | <pathology> Phagocyte that has ingested nuclear material of another cell: characteristic of systemic lupus erythematosus. (18 Nov 1997) |
|---|---|
| lupus erythematosus cell test | <investigation> A test for lupus that measures the presence of autoantibodies against nuclear proteins in the blood. Performed on a normal venipuncture specimen, this test is positive in 70 to 80% of patients with lupus. Some patients with rheumatoid arthritis, scleroderma and drug-induced lupus may also have a positive test result. (27 Sep 1997) |
| lupus erythematosus, cutaneous | A form of lupus erythematosus in which the skin may be the only organ involved or in which skin involvement precedes the spread into other body systems. It has been classified into three forms - acute (= lupus erythematosus, systemic with skin lesions), subacute, and chronic (= lupus erythematosus, discoid). (12 Dec 1998) |
| lupus erythematosus, discoid | A chronic form of cutaneous lupus erythematosus (lupus erythematosus, cutaneous) in which the skin lesions mimic those of the systemic form but in which systemic signs are rare. It is characterised by the presence of discoid skin plaques showing varying degrees of oedema, erythema, scaliness, follicular plugging, and skin atrophy. Lesions are surrounded by an elevated erythematous border. The condition typically involves the face and scalp, but widespread dissemination may occur. (12 Dec 1998) |
| lupus erythematosus profundus | A subcutaneous panniculitis with marked lymphocyte infiltration of fat lobules giving rise to deep-seated, firm, rubbery nodules that sometimes become ulcerated, usually of the face; may occur in systemic and localised lupus erythematosus. Synonym: lupus profundus. (05 Mar 2000) |
| lupus erythematosus, systemic | A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterised principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown aetiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of le cells in the blood or bone marrow. (12 Dec 1998) |
| lupus erythematosus test | <investigation> A test for lupus that measures the presence of autoantibodies against nuclear proteins in the blood. Performed on a normal venipuncture specimen, this test is positive in 70 to 80% of patients with lupus. Some patients with rheumatoid arthritis, scleroderma and drug-induced lupus may also have a positive test result. (27 Sep 1997) |
| lupus glomerulonephritis-pathology | Patient survival and preservation of renal function are predictable from renal pathology as demonstrated by biopsy and defined by the histological classification of the International Study of Kidney Disease in Children/World Health Organization (ISKDC/WHO). Semi-quantitative indices of nephron loss (chronicity index) and activity of acute potentially reversible inflammation (activity index) are not predictive of individual outcome, renal failure or death in patients with aggressively treated SLE GN. (05 Mar 2000) |
| lupus-like syndrome | <syndrome> A clinical syndrome resembling that of systemic lupus erythematosus, but due to some other cause. (05 Mar 2000) |
| lupus livido | Persistent cyanotic lesions on the extremities, associated with the cutaneous manifestations of Raynaud's disease. (05 Mar 2000) |
| lupus lymphaticus | A congenital nevoid lesion consisting of a circumscribed group of tense lymph vesicles. Synonym: lupus lymphaticus, lymphangiectodes, lymphangioma capillare varicosum, lymphangioma superficium simplex. (05 Mar 2000) |
| lupus mutilans | Cutaneous tuberculosis with extensive destruction of tissue. (05 Mar 2000) |
| lupus nephritis | Glomerulonephritis associated with systemic lupus erythematosus. It is classified into four histologic types: mesangial, focal, diffuse, and membranous. (12 Dec 1998) |
| lupus papillomatosus | A tuberculous skin lesion having a warty surface with a chronic inflammatory base seen on the hands in adults and lower extremities in children, with marked hypersensitivity to tuberculous antigens. See: postmortem wart. Synonym: lupus papillomatosus, lupus verrucosus, tuberculous wart, verrucous scrofuloderma. (05 Mar 2000) |
| lupus pernio | Sarcoid lesions, clinically resembling frostbite and microscopically resembling lupus vulgaris, involving ears, cheeks, nose, hands, and fingers. (05 Mar 2000) |