| ALP | acute leukemia protocol; acute lupus pericarditis; alkaline phosphatase; alveolar proteinosis; anter... |
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| BILAG | British Isles Lupus Assessment Group [Index] |
| CDLE | chronic discoid lupus erythematosus |
| DIL, Dil | Dilantin; drug-induced lupus [erythematosus] |
| DILE | drug-induced lupus erythematosus |
| lupus nephritis | Glomerulonephritis associated with systemic lupus erythematosus. It is classified into four histologic types: mesangial, focal, diffuse, and membranous. (12 Dec 1998) |
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| lupus papillomatosus | A tuberculous skin lesion having a warty surface with a chronic inflammatory base seen on the hands in adults and lower extremities in children, with marked hypersensitivity to tuberculous antigens. See: postmortem wart. Synonym: lupus papillomatosus, lupus verrucosus, tuberculous wart, verrucous scrofuloderma. (05 Mar 2000) |
| lupus pernio | Sarcoid lesions, clinically resembling frostbite and microscopically resembling lupus vulgaris, involving ears, cheeks, nose, hands, and fingers. (05 Mar 2000) |
| lupus profundus | A subcutaneous panniculitis with marked lymphocyte infiltration of fat lobules giving rise to deep-seated, firm, rubbery nodules that sometimes become ulcerated, usually of the face; may occur in systemic and localised lupus erythematosus. Synonym: lupus profundus. (05 Mar 2000) |
| lupus sebaceus | Lupus erythematosus with lesions on the face in butterfly areas. (05 Mar 2000) |
| lupus serpiginosus | A cutaneous tuberculous lesion that spreads peripherally, healing centrally with scar formation. (05 Mar 2000) |
| lupus superficialis | Skin disease in which there are red scaly patches, especially over the nose and cheeks. May be a symptom of systemic lupus erythematosus. (18 Nov 1997) |
| lupus tuberculosus | Cutaneous tuberculosis with characteristic nodular lesions on the face, particularly about the nose and ears. Synonym: lupus tuberculosus, tuberculosis cutis luposa. (05 Mar 2000) |
| lupus verrucosus | A tuberculous skin lesion having a warty surface with a chronic inflammatory base seen on the hands in adults and lower extremities in children, with marked hypersensitivity to tuberculous antigens. See: postmortem wart. Synonym: lupus papillomatosus, lupus verrucosus, tuberculous wart, verrucous scrofuloderma. (05 Mar 2000) |
| lupus vulgaris | Cutaneous tuberculosis with characteristic nodular lesions on the face, particularly about the nose and ears. Synonym: lupus tuberculosus, tuberculosis cutis luposa. (05 Mar 2000) |
| a1-trypsin inhibitor | A glycoprotein that is the major protease inhibitor of human serum, is synthesised in the liver, and is genetically polymorphic due to the presence of over 20 alleles; individuals appropriately homozygous are deficient in a1-trypsin and are predisposed to pulmonary emphysema and juvenile hepatic cirrhosis because of alterations in the amino acid and sialic acid components of the glycoprotein. A1-Antitrypsin also inhibits thrombin. Synonym: a1-trypsin inhibitor, human a1-proteinase inhibitor. (05 Mar 2000) |
| ACE inhibitor | <pharmacology> A group of antihypertensive medications that work by inhibiting an enzyme (angiotensin-converting enzyme) that is important in the regulation of blood pressure. Studies have also indicated that it may help prevent or slow the progression of kidney disease in patients with diabetes. Examples include: captopril, ramipril, enalapril, losartan potassium, bepridil and lisinopril. (12 Mar 1998) |
| aldose reductase inhibitor | <pharmacology> A class of drugs being studied as a way to prevent eye and nerve damage in people with diabetes. Aldose reductase is an enzyme that is normally present in the eye and in many other parts of the body. It helps change glucose (sugar) into a sugar alcohol called sorbitol. Too much sorbitol trapped in eye and nerve cells can damage these cells, leading to retinopathy and neuropathy. Drugs that prevent or slow (inhibit) the action of aldose reductase are being studied as a way to prevent or delay these complications of diabetes. (09 Oct 1997) |
| angiotensin-converting enzyme inhibitor | <pharmacology> A class of drugs used in the treatment of hypertension and heart failure. They exert their haemodynamic effect mainly by inhibiting the renin-angiotensin system and produce a reduction of peripheral arterial resistance. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility. (14 Aug 2000) |
| aromatase inhibitor | Drugs, such as aminoglutethimide, that inhibit aromatase, an enzyme used in the synthesis of oestrogens. (05 Mar 2000) |