| leishmaniasis recidivans | A partially healing leishmanial lesion caused by Leishmania tropica and characterised by an extreme form of cellular immune response, intense granuloma production, fibrinoid necrosis without caseation, and frequent development of satellite lesions that continue the production of granulomatous tissue without healing, sometimes over a period of many years; organisms are difficult to demonstrate but can be cultured. Synonym: lupoid leishmaniasis. (05 Mar 2000) |
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| leishmaniasis tegumentaria diffusa | Leishmaniasis caused by several New and Old World species and strains of Leishmania (L. Mexicana amazonensis, L. M. Pifanoi, possibly L. M. Garnhami and L. M. Venezuelensis; in Ethiopia, L. Aethiopica, and unidentified leishmanial agents in Namibia and Tanzania). The condition is associated with a suppressed cell-mediated immune response, so that the non-ulcerating, non-necrotizing cutaneous lesions can spread widely over the body; great numbers of parasite-filled macrophages are found in the dermal lesions. Healing does not appear to occur unless an acquired cellular hypersensitivity can develop. Synonym: anergic leishmaniasis, diffuse leishmaniasis, disseminated cutaneous leishmaniasis, leishmaniasis tegumentaria diffusa, pseudolepromatous leishmaniasis. (05 Mar 2000) |
| leishmaniasis, visceral | A chronic disease caused by leishmania donovani and transmitted by the bite of several sandflies of the genera phlebotomus and lutzomyia. It is commonly characterised by fever, chills, vomiting, anaemia, hepatosplenomegaly, leukopenia, hypergammaglobulinaemia, emaciation, and an earth-gray colour of the skin. The disease is classified into three main types according to geographic distribution: indian, mediterranean (or infantile), and african. (12 Dec 1998) |