| sex-linked character | An inherited character determined by a gene on a gonosome. See: gene. (05 Mar 2000) |
|---|---|
| sex-linked inheritance | The pattern of inheritance that may result from a mutant gene located on either the X or Y chromosome. (05 Mar 2000) |
| sex-linked locus | Any locus that in normal karyotypes is borne on a heterosome; commonly but incorrectly applied to an X-linked locus. (05 Mar 2000) |
| N-acetylated-alpha-linked acidic dipeptidase | <enzyme> Chloride-dependent membrane bound metallopeptidase, most active with the endogenous neuropeptide n-acetyl-l-aspartyl-l-glutamate Registry number: EC 3.4.13.- Synonym: naaladase, glutamate carboxypeptidase II, prostate-specific membrane antigen, psm antigen (26 Jun 1999) |
| ichthyosis, x-linked | Chronic form of ichthyosis that is inherited as a sex-linked recessive trait carried on the x-chromosome and transmitted to the male offspring. It is characterised by severe scaling, especially on the extremities, and is associated with steroid sulfatase deficiency. (12 Dec 1998) |
| integrated rate expression | An equation of a chemical or enzyme-catalyzed reaction for the entire progress curve. (05 Mar 2000) |
| oocyte expression | <molecular biology> Technique whereby the cellular machinery of an oocyte (typically that of Xenopus) is utilised to transcribe functional protein from microinjected RNA. (18 Nov 1997) |
| enzyme-linked immunoabsorbent assay | <investigation> The enzyme-linked immunoabsorbent assay is serologic test used as a general screening tool for the detection of antibodies to the HIV virus. Reported as positive or negative. Since false positive tests due occur (for example recent flu shot), positives will require further evaluation using the western blot. ELISA technology links an a measurable enzyme to either an antigen or antibody. In this way, it can then measure the presence of an antibody or an antigen in the bloodstream. Acronym: ELISA (27 Sep 1997) |
| enzyme-linked immunosorbent assay | An immunoassay utilizing an antibody labelled with an enzyme marker such as horseradish peroxidase. While either the enzyme or the antibody is bound to an immunosorbent substrate, they both retain their biologic activity; the change in enzyme activity as a result of the enzyme-antibody-antigen reaction is proportional to the concentration of the antigen and can be measured spectrophotometrically or with the naked eye. Many variations of the method have been developed. (12 Dec 1998) |
| expression | <molecular biology> The process by which a gene's coded information is converted into the structures present and operating in the cell. Expressed genes include those that are transcribed into mRNA and then translated into protein and those that are transcribed into RNA but not translated into protein (for example, transfer and ribosomal RNAs). (06 Aug 1998) |
| expression cloning | <molecular biology> A vector that results in the expression of inserted DNA sequences when propagated in a suitable host cell, i.e. The protein coded for by the DNA is synthesised by the host's system. (06 Aug 1998) |
| expression library | <molecular biology> A library of DNA fragments which was created with an expression vector so that any genes present in the library are expressed. (09 Oct 1997) |
| expression site | The location in the genome of the gene for the variable surface glycoprotein that is currently being expressed (an expression-linked copy) by the trypanosome (a parasitic protozoan which causes the disease African sleeping sickness). most of these sites are near the ends, or telomeres, of a chromosome. (09 Oct 1997) |
| expression system | <molecular biology> Combination of an expression vector, its cloned DNA, and the host for the vector that provide a context to allow foreign gene function in a host cell, that is, produce proteins at a high level. (13 Nov 1997) |
| expression vector | <molecular biology> A cloning vector that contains the necessary regulatory sequences to allow transcription and translation of a cloned gene or genes and thus transcribe and clone DNA. (13 Nov 1997) |