| insulin-like growth factor binding protein 3 | One of the six homologous soluble proteins that bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions at the cellular level. (12 Dec 1998) |
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| insulin like growth-factor-binding protein 4 | One of the six homologous soluble proteins that bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions at the cellular level. (12 Dec 1998) |
| insulin-like growth-factor-binding-protein 5 | One of the six homologous soluble proteins that bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions at the cellular level. (12 Dec 1998) |
| insulin-like-growth-factor-binding protein 6 | One of the six homologous soluble proteins that bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions at the cellular level. (12 Dec 1998) |
| insulin-like growth-factor-binding proteins | A family of soluble proteins that bind insulin-like growth factors and modulate their biological actions at the cellular level. (int j gynaecol obstet 1992;39(1):3-9) (12 Dec 1998) |
| insulin-like growth factor I | <chemical> A well-characterised basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on somatotropin. It is believed to be mainly active in adults in contrast to insulin-like growth factor II, which is a major foetal growth factor. Chemical name: Insulin-like growth factor I (12 Dec 1998) |
| insulin-like growth factor II | <chemical> A well-characterised neutral peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on somatotropin. It is believed to be a major foetal growth factor in contrast to insulin-like growth factor I, which is a major growth factor in adults. Chemical name: Insulin-like growth factor II (12 Dec 1998) |
| insulin-like growth factors | Peptides whose formation is stimulated by growth hormone. These peptides bring about peripheral tissue effects of that hormone and have high (about 70%) homology to human insulin. Synonym: somatomedins. (05 Mar 2000) |
| thogoto-like viruses | A genus of the family orthomyxoviridae comprising tick-borne viruses occasionally infecting humans. Dhori and thogoto viruses were formerly thought to be members of bunyaviridae. Thogoto virus is the type species. (12 Dec 1998) |
| EGF like domain | Region of 30-40 amino acids containing 6 cysteines found originally in EGF and also in a range of proteins involved in cell signalling. Examples: TGF _, amphiregulin, urokinase, tissue plasminogen activator, complement C6 C9, fibronectin, laminin (each subunit at least 13 times), nidogen, selectins. It is also found in the Drosophila gene products: Notch (36 times) Delta, Slit, Crumbs, Serrate. (18 Nov 1997) |
| enterochromaffin-like cells | Irregular-shaped argyrophilic cells which produce histamine, chromogranin a/pancreastatin, and an as yet unidentified peptide hormone. They are the predominant endocrine cell type of the oxyntic (acid-producing) mucosa of the stomach. Ecl cells respond to gastrin by releasing their secretory products and this source of histamine acts as the positive paracrine stimulator of the release of hydrochloric acid from the parietal cell. (12 Dec 1998) |
| fibroblast growth factor receptor-like embryonic kinase | <enzyme> Found in avian embryonic tissue; involved in early differentiation of skeletal muscle. Registry number: EC 2.7.1.- Synonym: frek (26 Jun 1999) |
| lichen planus-like keratosis | A solitary benign papule or plaque, with microscopic features resembling lichen planus, occurring on sun-exposed or unexposed skin. Synonym: lichen planus-like keratosis. (05 Mar 2000) |
| lupus-like syndrome | <syndrome> A clinical syndrome resembling that of systemic lupus erythematosus, but due to some other cause. (05 Mar 2000) |