| carboxyl-terminal residue | This amino acid residue defines the carboxylterminus of the polypeptide, its the only residue with a free alpha-carboxyl group. (09 Oct 1997) |
|---|---|
| carboxy terminal | The end of a peptide or protein having a free carboxyl (-COOH) group. (05 Mar 2000) |
| carboxy-terminal domain kinase | <enzyme> Protein kinase that phosphorylates the c-terminal repeat domain of the largest subunit of RNA polymerase II at serine residues Registry number: EC 2.7.1.- Synonym: ctd kinase, hs-ctd kinase, tfiih-associated ctd kinase (26 Jun 1999) |
| central terminal electrode | In electrocardiography, an electrode in which connections from the three limbs (right arm, left arm, and left leg) are joined and led to the electrocardiograph to form the indifferent electrode, theoretically at zero potential for the system. (05 Mar 2000) |
| RNA 3'-terminal phosphate cyclase | <enzyme> ATP dependent; forms 2',3' terminal cyclic phosphate on RNA which is then the substrate for RNA ligase of hela cells Registry number: EC 6.5.- Synonym: RNA tph cyclase (26 Jun 1999) |
| c-Jun amino-terminal kinase | <enzyme> A stress-activated protein kinase; 46-kD kinase that phosphorylates ser(63) and ser(73) of c-jun; similar to yeast hog1 kinase; amino acid sequence given in second source; genbank l23118 Registry number: EC 2.7.10.- Synonym: jn kinase, jnk1 protein kinase, jnk-46, jnk1 protein, jun-nh2-terminal kinase, stress-activated protein kinase 1, sap kinase-1, sapk1, p46 sap kinase, c-jun kinase-1 (26 Jun 1999) |
| photosystem II D1 polypeptide carboxy-terminal processing protease | <enzyme> From thylakoids; not inhibited by common protease inhibitors Registry number: EC 3.4.99.- Synonym: d1 carboxy-terminal processing protease, d1 c-terminal protease, ctpa gene product (26 Jun 1999) |
| COOH-terminal signal transamidase | <enzyme> Present in the endoplasmic reticulum; catalyses concomitant cleavage of the signal peptide of nascent proteins destined to be processed to a glycosylphosphatidylinositol (gpi) and addition of the gpi anchor Registry number: EC 2.3.2.- Synonym: cooh-ts-transamidase, gpi transamidase, gpti transamidase (26 Jun 1999) |
| C-terminal leucine protein methyltransferase | <enzyme> Reversibly modifies protein phosphatase 2a by methyl esterification at its c-terminal leucine residues Registry number: EC 2.1.1.- Synonym: tlp methyltransferase (26 Jun 1999) |
| protein NH2-terminal asparagine deamidase | <enzyme> Converts amino terminal asparagine to aspartic acid; from porcine liver; mw about 33 kD Registry number: EC 3.5.1.- Synonym: porcine pnad (26 Jun 1999) |
| protein N-terminal acetyltransferase | <enzyme> From saccharmyces cerevisiae; encodes a catalytic subunit of an n-terminal acetyltransferase; ard1 and nat1 proteins are subunits of this enzyme Registry number: EC 2.3.1.- Synonym: nat1 gene protein, saccharomyces, yeast protein n-terminal acetyltransferase, n-terminal protein acetyltransferase, ard1 protein (26 Jun 1999) |
| small bowel disease involving terminal ileum | <radiology> Crohn's, TB, Yersinia (12 Dec 1998) |
| NH2-terminal | <biochemistry> The end of a protein or polypeptide chain with the unattached amino group or the aminoacyl residue containing it. Each amino acid in the chain has an amino group on one side, which is attached to the carboxyl group (COOH group) of the previous amino acid, and a carboxyl group on the other side (which is attached to the amino group of the next amino acid). The other end of the polypeptide chain is called the carboxyl terminal. Synonym: NH2-terminal. (14 Aug 2000) |
| Deiters' terminal frames | Platelike structures in the organ of Corti uniting the outer phalangeal cells with Hensen's cells. (05 Mar 2000) |
| ileitis, terminal | Crohn's disease, a chronic inflammatory disease of the intestine involving only the end of the small intestine (the terminal ileum). Crohn's disease affects primarily the small and large intestines but which can occur anywhere in the digestive system between the mouth and the anus. Named after burrill crohn who described the disease in 1932. The disease often strikes persons in their teens or early twenties. It tends to be chronic, recurrent with periods of remission and exacerbation. In the early stages. It causes small scattered shallow crater-like areas (erosions) called apthous ulcers in the inner surface of the bowel. With time, deeper and larger ulcers develop, causing scarring and stiffness of the bowel and the bowel becomes increasingly narrowed, leading to obstruction. Deep ulcers can puncture holes in the bowel wall, leading to infection in the abdominal cavity (peritonitis) and in adjacent organs abdominal pain, diarrhoea, vomiting, fever, and weight loss can be symptoms. Crohn's disease can be associated with reddish tender skin nodules, and inflammation of the joints, spine, eyes, and liver. Diagnosis is by barium enema, barium X-ray of the small bowel, and colonoscopy. Treatment includes medications for inflammation, immune suppression, antibiotics, or surgery. (12 Dec 1998) |