| cell adhesion molecules, neuronal | Surface ligands that mediate cell-to-cell adhesion and function in the assembly and interconnection of the vertebrate nervous system. These molecules promote cell adhesion via a homophilic mechanism. These are not to be confused with ncam (neural cell adhesion molecule), now known to be expressed in a variety of tissues and cell types in addition to nervous tissue. (12 Dec 1998) |
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| cell adhesion molecules, neuron-glia | Cell adhesion molecules that mediate neuron-neuron adhesion and neuron-astrocyte adhesion. They are expressed on neurons and schwann cells, but not astrocytes and are involved in neuronal migration, neurite fasciculation, and outgrowth. Ng-cam is immunologically and structurally distinct from ncam (neural cell adhesion molecules). (12 Dec 1998) |
| water of adhesion | Water held by molecular attraction in contact with solid surfaces, but not forming an essential part of their constitution. (05 Mar 2000) |
| primary adhesion | Healing by fibrous adhesion, without suppuration or granulation tissue formation. Synonym: primary adhesion, primary union. (05 Mar 2000) |
| secondary adhesion | Delayed closure of two granulating surfaces. Synonym: secondary adhesion, secondary union. (05 Mar 2000) |
| differential adhesion | The differential adhesion hypothesis was advanced by Steinberg to explain the mechanism by which heterotypic cells in mixed aggregates sort out into isotypic territories. Quantitative differences in homo and hetero typic adhesion are supposed to be sufficient to account for the phenomenon without the need to postulate cell type specific adhesion systems: fairly generally accepted, although some tissue specific cell adhesion molecules are now known to exist. (18 Nov 1997) |
| immune adhesion test | The diagnostic application of the immune adhesion phenomenon. Synonym: erythrocyte adherence test, immune adhesion test, red cell adherence test. (05 Mar 2000) |
| interthalamic adhesion | The variable connection between the two thalamic masses across the third ventricle; absent in about 20% of human brains. Synonym: adhesio interthalamica, commissura cinerea, commissura grisea, intermediate mass, massa intermedia. (05 Mar 2000) |
| fibrinous adhesion | An adhesion that consists of fine threads of fibrin resulting from an exudate of plasma or lymph, or an extravasation of blood. (05 Mar 2000) |
| fibrous adhesion | Fibrous strands resulting from the organization of fibrinous adhesion's. (05 Mar 2000) |
| focal adhesion | <cell biology> Areas of close apposition and thus presumably anchorage points, of the plasma membrane of a fibroblast (for example) to the substratum over which it is moving. Usually 1m x 0.2 m with the long axis parallel to the direction of movement, always associated with a cytoplasmic microfilament bundle that is attached via several proteins to the plasma membrane at an area of high protein concentration (this is noticeably electron dense in electron micrographs). Focal adhesions tend to be characteristic of slow moving cells. (18 Nov 1997) |
| leukocyte adhesion deficiency | An inherited disorder (autosomal recessive) in which there is a defective CD18 adherence complex that disturbs leukocyte chemotaxis. It is characterised by recurrent bacterial infections and impaired wound healing. (05 Mar 2000) |
| leukocyte-adhesion deficiency syndrome | <syndrome> Rare, autosomal recessive disorder caused by deficiency of the beta 2 integrin receptors (receptors, leukocyte-adhesion) comprising the CD11/CD18 family of glycoproteins. The syndrome is characterised by abnormal adhesion-dependent functions, especially defective tissue emigration of neutrophils, leading to recurrent infection. (12 Dec 1998) |