| IAFI | infantile amaurotic familial idiocy |
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| IBSN | infantile bilateral striated necrosis |
| ICP | incubation period; indwelling catheter program; infantile cerebral palsy; infection-control practiti... |
| IDBS | infantile diffuse brain sclerosis |
| IGA | infantile genetic agranulocytosis |
| infantile gastroenteritis virus | <virology> Genus of the Reoviridae having a double layered capsid and 11 double stranded RNA molecules in the genome. They have a wheel like appearance in the electron microscope and cause acute diarrhoeal disease in their mammalian and avian hosts. Probably the most important cause of severe dehydrating diarrhoea in children under three years of age worldwide. Symptoms include nausea, vomiting, low-grade fever and diarrhoea. Aggressive fluid replacement is generally required. (27 Sep 1997) |
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| infantile generalised GM1 gangliosidosis | One of the hereditary metabolic diseases of infancy; resembles Tay-Sachs disease, except other organ systems (bone, liver, kidney) are affected. Synonym: familial neuroviscerolipidosis, pseudo-Hurler disease, Type 1 GM1 gangliosidosis. (05 Mar 2000) |
| infantile GM2 gangliosidosis | <disease> A genetic disorder found in east European Jewish families which can result in early death bu affecting the brain and nerves by causing abnormal lipid metabolism. It is a lysosomal disease in which there is a deficiency of hexosaminidase A, an enzyme that degrades ganglioside GM2. Symptoms appear at age 3-6 months and include blindness, deafness, seizures, paralysis, dementia, decreased muscle tone and growth retardation. There is no known treatment and most children usually die between 2 and 5 years of age. Inheritance: autosomal recessive. (06 Oct 1997) |
| infantile hemiplegia | Indefinite term for any motor abnormality in the infant caused by or attributed to the birthing process; includes obstetrical paralysis, infantile hemiplegia, etc. Synonym: infantile hemiplegia. (05 Mar 2000) |
| infantile hernia | A hernia in which an intestinal loop descends behind the tunica vaginalis, having, therefore, three peritoneal layers in front of it. (05 Mar 2000) |
| infantile hydrocephalus | <radiology> A VP-Shunt Can Decompress The Hydrocephalic Child, Aqueductal stenosis, Vein of Galen aneurysm, Postinfectious, Superior vena cava obstruction, Chiari malformation, Dandy-Walker syndrome, Tumour, Haemorrhage, Choroid plexus papilloma see: hydrocephalus (12 Dec 1998) |
| infantile hypothyroidism | <paediatrics> Stunted body growth and mental development appearing in the first years of life resulting the inappropriate development of the thymus gland or inadequate maternal intake of iodine during gestation. (27 Sep 1997) |
| infantile leishmaniasis | Visceral leishmaniasis in infants, from Leishmania donovani infantum. (05 Mar 2000) |
| infantile muscular atrophy | Transmitted as autosomal recessive on chromosome 5q. Progressive dysfunction of the anterior horn cells in the spinal cord and brainstem cranial nerves with profound weakness and bulbar dysfunction occurring in the first two years of life. Three groups, based on age of clinical onset, are recognised. Synonym: familial spinal muscular atrophy, Hoffmann's muscular atrophy, infantile muscular atrophy, infantile progressive spinal muscular atrophy, progressive infantile spinal muscular atrophy, Werdnig-Hoffmann disease, Werdnig-Hoffmann muscular atrophy. (05 Mar 2000) |
| infantile myxoedema | <paediatrics> Stunted body growth and mental development appearing in the first years of life resulting the inappropriate development of the thymus gland or inadequate maternal intake of iodine during gestation. (27 Sep 1997) |
| infantile neuroaxonal dystrophy | <neurology, paediatrics> A rare, familial disorder of early childhood manifested as progressive psychomotor deterioration, increased reflexes, Babinski sign, hypotonia and progressive blindness. Pathologically, eosinophilic spheroids of swollen axoplasm are found in various central nervous system nuclei. (05 Mar 2000) |
| infantile neuronal degeneration | <neurology, paediatrics> Degenerative disorder of infants with widespread neuronal loss in thalamus, cerebellum, pons, and spinal cord, resembling infantile muscular atrophy. (05 Mar 2000) |
| infantile osteomalacia | <rheumatology, orthopaedics> A condition caused by deficiency of vitamin D, especially in infancy and childhood, with disturbance of normal ossification. The disease is marked by bending and distortion of the bones under muscular action, by the formation of nodular enlargements on the ends and sides of the bones, by delayed closure of the fontanelles, pain in the muscles and sweating of the head. Vitamin D and sunlight together with an adequate diet are curative, provided that the parathyroid glands are functioning properly. Origin: Gr. Rhachitis = a spinal complaint (18 Nov 1997) |
| infantile paralysis | Old synonym for polio. (12 Dec 1998) |
| infantile pellagra | A nutritional deficiency illness in children who are not getting enough protein, this results in anaemia, poor growth, weakness, and oedema (which isparticularly characterised by a pronounced pot belly). Infamine-stricken regions, children typically develop kwashiorkor rightafter they are weaned. (09 Oct 1997) |