| idiotypeanti-idiotype n. |
a regulatory mechanism mounted in response to the unique or idiotypic determinants of lymphocytes or antibodies upon antigenic stimulation. Activation of a B cell results in a clone of plasma cells producing immunoglobulin of a single idiotype, which, because it was previously present in very small quantities, can be recognized as “nonself” and results in the production of anti-idiotypic antibodies directed against its idiotypic determinants. There can also be antianti-idiotypic antibodies directed against the second antibodies, antibodies directed against them, and so forth. These antibodies react with antigen receptors on B cells and T helper and suppressor cells, as well as with circulating antibodies, to enhance or suppress production of the initial antibody by various mechanisms.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| idiotypic |
pertaining to idiotypes.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| idiotypic v. |
the antigenic differences that characterize the different amino acid sequences and structures of immunoglobulin variable regions (idiotypes) and corresponding differences in antigen specificity.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| idiot |
Intrusion Detection In Our Time. A system that detects intrusions using pattern-matching.
Ãâó: www.tsl.state.tx.us/ld/pubs/compsecurity/glossary....
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| idiotope |
idi?opo. Ep?opo o determinante antig?ico situado en las regiones variables de las cadenas livianas y pesadas (V H yV L , respectivamente) de un anticuerpo (en la zona de contacto con el ant?eno o alrededor de esta zona). Es sin?imo de determinante idiot?ico. V?nse ANTIBODY e IDIOTYPE.
Ãâó: www.medtrad.org/biblioteca/referencia/glosario/I.h...
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