| 영문 | gene therapy | 한글 | 유전자요법 |
|---|---|---|---|
| 설명 | 유전병을 치료할 목적으로, 정상적으로 기능하는 단일유전자 혹은 복수유전자를 어떤 기원에서 얻어내어 생세포에 도입하는 것. 유전물질은 유전자삽입 조작에 의해 수용세포에로 도입된다. 즉, 유전자를 끼워 넣은 새로운 세포를 사용하는 치료로서 1980년 미국의 학자가 지중해빈혈환자에게 강행하여 비판을 받았지만, 미국 국립보건연구소는 1990년 9월 아데노신 데아미나아제(adenosine deaminase, ADA) 결핍증 환자의 림프구에 ADA 유전자를 끼워 넣는 치료를 시작한 이래 현재는 암을 포함한 많은 질병들을 치료하는 목적으로 쓰인다. |
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| 영문 | Electric convulsive therapy(ECT) | 한글 | 전기경련요법 |
|---|---|---|---|
| 설명 | 뇌에 전기 자극을 주어 인위적으로 경련을 유발함으로써 정신 병을 치료하는 방법. 전기쇼크요법(electroshock therapy)이라고도 한다. 1938년에 이탈리아의 체를레티와 비니에 의해 시작되었다. 작용기전은 확실치 않으나 뇌의 신진대사, 생화학 및 효소 등에 변화를 일으킨다는 생물학적, 생화학적 학설이 유력하다. 적응증으로 가장 효과적인 병은 우울증으로 특히 여성에서 갱년기에 호발하는 갱년기 우울증, 우울증과 조증(아주 기분이 좋은 상태가 지속되는 정신병)이 일정한 주기를 두고 반복하는 조울증에 잘 쓰이며, 80~90%에서 효과가 있다. |
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| AART | American Association for Rehabilitation Therapy; American Association for Respiratory Therapy |
|---|---|
| ACT | achievement through counseling and treatment; actin; actinomycin; activated clotting time; advanced ... |
| ERT | esophageal radionuclide transit; estrogen replacement therapy; examination room terminal; external r... |
| ICT | icteric, icterus; indirect Coombs test; inflammation of connective tissue; insulin coma therapy; int... |
| OT | objective test; oblique talus; occlusion time; occupational therapist, occupational therapy; ocular ... |
| active site | <chemistry> A specific region of an enzyme where a substrate binds and catalysis takes place (binding site). (06 May 1997) |
|---|---|
| active splint | A splint utilizing springs or elastic bands that aids in movements initiated by the patient by controlling the plane and range of motion. Synonym: active splint, functional splint. (05 Mar 2000) |
| active succinate | The condensation product of succinic acid and CoA; one of the intermediates of the tricarboxylic acid cycle and a precursor in the synthesis of haem. Synonym: active succinate, succinyl-CoA. (05 Mar 2000) |
| active sulfate | 3'-phosphoadenosine 5'-phosphosulfate;an intermediate in the formation of urinary ethereal sulfates, notable for containing a "high energy" sulfate bond; the 3'-OH of adenosine is replaced by -OPO3H2, the 5'-OH by -OP(O2H)-OSO3H. Synonym: active sulfate. Acronym: PAPS (05 Mar 2000) |
| active transport | <biochemistry, chemistry> Transport of ions, nutrients or other molecules into a cell against a concentration gradient, this requires the expenditure of energy through ATP hydrolysis. (06 May 1997) |
| active treatment | A therapeutic substance or course intended to ameliorate the basic disease problem, as opposed to supportive or palliative treatment. Compare: causal treatment. (05 Mar 2000) |
| active vasoconstriction | Reduced caliber of a vessel caused by increased tonus in the smooth muscle in its walls. (05 Mar 2000) |
| active vasodilation | Vasodilation caused by decrease in tonus of smooth muscle in the wall of a vessel. (05 Mar 2000) |
| artificial active immunity | See: acquired immunity. (05 Mar 2000) |
| biological transport, active | The movement of materials across cell membranes and epithelial layers against an electrochemical gradient, requiring the expenditure of metabolic energy. (12 Dec 1998) |
| chronic active hepatitis | <pathology> This is a form of continuing liver inflammation that results in liver cell death. Causes include viral infection (hepatitis D, hepatitis B, hepatitis C), autoimmune disease, drug ingestion or metabolic causes. Chronic active hepatitis will lead to hepatic failure and death in a small percentage of these patients. (27 Sep 1997) |
| chronic active inflammation | The coexistence of chronic inflammation and superimposed acute inflammation. (05 Mar 2000) |
| chronic active liver disease | Any of several types of hepatitis persisting for more than six months, often progressing to cirrhosis. Synonym: chronic active liver disease. (05 Mar 2000) |
| specific active immunity | See: acquired immunity. (05 Mar 2000) |
| surface-active | Indicating the property of certain agents of altering the physicochemical nature of surfaces and interfaces, bringing about lowering of interfacial tension; they usually possess both lipophilic and hydrophilic groups. See: surfactant. (05 Mar 2000) |