| endocardial cushion defect | <radiology> Persistence of primitive atrioventricular canal and anomalies of AV valves associated with: Down syndrome: in 25% of Trisomy 21 an ECD is present; in 45% of ECD Trisomy 21 is present, asplenia/polysplenia types: complete (AV canal), partial findings: gooseneck deformity on angiogram, increased pulmonary vascularity, enlarged pulmonary artery, enlarged RV, LV, RA; normal LA (secondary to atrial septal defect) (12 Dec 1998) |
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| enzyme defect | A disorder resulting from a deficiency (or functional abnormality) of an enzyme. In 1902 Archibald Garrod first attributed a disease to an enzyme defect: an inborn error of metabolism. Today, newborns are routinely screened for certain enzyme defects such as PKU (phenylketonuria) and galactosaemia, an error in the handling (metabolism) of the sugar galactose. (12 Dec 1998) |
| fibrous cortical defect | A common 1 to 3 cm defect in the cortex of a bone, most commonly the lower femoral shaft of a child, filled with fibrous tissue. Nonosteogenic or nonossifying fibroma by convention refers to lesions greater than 3 cm in diameter. See: nonossifying fibroma. Synonym: nonosteogenic fibroma. (05 Mar 2000) |
| uterine filling defect | <radiology> Technical, bubble, blood clot, mucoid material, congenital fold, pseudoadhesions / ridging -- folds long axis, neoplasm, submucosal leiomyoma, adenoma, endometrial carcinoma, pregnancy-related, pregnancy, molar pregnancy, retained conceptus, polyp, septated uterus, synechiae, IUD, iatrogenic (post-op) (12 Dec 1998) |
| filling defect | Displacement of contrast medium by a space-occupying lesion in a radiographic study of a contrast-filled hollow viscus, such as a polyp on a barium enema; also applied to defects in the otherwise uniform distribution of radionuclide in an organ, such as a metastasis in the liver on a 99mTc-sulfur colloid scan. (05 Mar 2000) |
| filling defect in renal collecting system | <radiology> Common causes: transitional cell carcinoma, blood clot, lucent calculus (urate) less common causes: fungus ball, sloughed papilla, fibroepithelial polyp, invasion by hypernephroma, malakoplakia, vessel impression, metastases (12 Dec 1998) |
| lambdoid suture defect | <radiology> Well-defined lucent lesion, classically unilateral, associated with neurofibromatosis (12 Dec 1998) |
| luteal phase defect | Inadequate function of the corpus luteum that may prevent a fertilized egg from implanting in the uterus or may lead to early pregnancy loss. (09 Oct 1997) |
| abnormal heart chamber dimensions | <radiology> Left ventricular volume overload, left ventricular hypertrophy, right ventricular volume overload, right ventricular hypertrophy, fixed subvalvular aortic stenosis, hypoplastic left/right ventricle; common ventricle, congestive cardiomyopathy (12 Dec 1998) |
| Abrams' heart reflex | A contraction of the myocardium when the skin of the precordial region is irritated. (05 Mar 2000) |
| american heart association | A voluntary organization concerned with the prevention and treatment of heart and vascular diseases. (12 Dec 1998) |
| apex of heart | The blunt extremity of the heart formed by the left ventricle. See: apex beat. Synonym: apex cordis, vertex cordis. (05 Mar 2000) |
| armored heart | Calcareous deposits in the pericardium due to subacute or chronic pericarditis. Synonym: panzerherz. (05 Mar 2000) |
| armor heart | Extensive to complete calcification (rarely ossification) of the pericardium usually producing constrictive pericarditis. (05 Mar 2000) |
| artificial heart | A mechanical pump used to replace the function of a damaged heart, either temporarily or as a permanent prosthesis. (05 Mar 2000) |