| NBT test | Nitro-Blue Tetrazolium (dye reduction) test ; Chronic Granulomatous Disease진단에 사용... |
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| CDER | Center for Drug Evaluation and Research; chronic granulomatous disease |
| CGD | chronic granulomatous disease |
| FGD | fatal granulomatous disease |
| GANS | granulomatous angiitis of the nervous system |
| chronic inflammation | An inflammation that may begin with a relatively rapid onset or in a slow, insidious, and even unnoticed manner, tends to persist for several weeks, months, or years and has a vague and indefinite termination; results when the injuring agent (or products resulting from its presence) persists in the lesion, and the host's tissues respond in a manner (or to a degree) that is not sufficient to overcome completely the continuing effects of the injuring agent. (05 Mar 2000) |
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| productive inflammation | A vague term ordinarily used with reference to proliferative inflammation, with or without an exudate; also sometimes used to indicate any inflammation in which grossly visible exudate is formed. (05 Mar 2000) |
| proliferative inflammation | An inflammatory reaction in which the distinguishing feature is an actual increase in the number of tissue cells, especially the reticuloendothelial macrophages, in contrast to cells exuded from blood vessels; in addition, exudates of various types are likely to be observed in granulomas and other forms of proliferative inflammation, but the latter may occur without an exudate being formed (as in certain infections caused by virus). Synonym: hyperplastic inflammation. (05 Mar 2000) |
| sclerosing inflammation | Inflammation leading to extensive formation of fibrous and scar tissue. (05 Mar 2000) |
| pseudomembranous inflammation | A form of exudative inflammation that involves mucous and serous membranes; relatively large quantities of fibrin in the exudate result in a rather tenacious membrane-like covering that is fairly adherent to the underlying acutely inflamed tissue; the pseudomembrane usually contains (in addition to the dense network of fibrin) varying quantities of plasma protein, degenerated and necrotic elements from the affected tissue, polymorphonuclear leukocytes, bacteria, etc. (05 Mar 2000) |
| purulent inflammation | An acute exudative inflammation in which the accumulation of polymorphonuclear leukocytes is sufficiently great that their enzymes cause liquefaction of the affected tissues, focally or diffusely; the purulent exudate is frequently termed pus, and consists of plasma and its constituents, end products of the enzymatic digestion of tissue, degenerated and necrotic cells and their debris, polymorphonuclear leukocytes and other white blood cells, the causal agent of the inflammation, etc. Synonym: suppurative inflammation. (05 Mar 2000) |
| serofibrinous inflammation | Inflammation in which the exudate consists chiefly of serous fluid with an unusually large proportion of fibrin. (05 Mar 2000) |
| serous inflammation | An exudative inflammation in which the exudate is predominantly fluid (e.g., exuded from the blood vessels), with the protein, electrolytes, and other material contained therein; relatively few (if any) cells are observed. (05 Mar 2000) |
| hyperplastic inflammation | An inflammatory reaction in which the distinguishing feature is an actual increase in the number of tissue cells, especially the reticuloendothelial macrophages, in contrast to cells exuded from blood vessels; in addition, exudates of various types are likely to be observed in granulomas and other forms of proliferative inflammation, but the latter may occur without an exudate being formed (as in certain infections caused by virus). Synonym: hyperplastic inflammation. (05 Mar 2000) |
| necrotic inflammation | Usually an acute inflammatory reaction in which the predominant histologic change is fairly rapid necrosis that occurs diffusely or extensively in relatively large foci throughout the affected tissue, frequently with only little or no evidence of cells in the exudate. (05 Mar 2000) |
| subacute inflammation | An inflammation that is intermediate in duration between that of an acute inflammation and that of a chronic inflammation, usually persisting longer than 3 or 4 weeks. (05 Mar 2000) |
| suppurative inflammation | An acute exudative inflammation in which the accumulation of polymorphonuclear leukocytes is sufficiently great that their enzymes cause liquefaction of the affected tissues, focally or diffusely; the purulent exudate is frequently termed pus, and consists of plasma and its constituents, end products of the enzymatic digestion of tissue, degenerated and necrotic cells and their debris, polymorphonuclear leukocytes and other white blood cells, the causal agent of the inflammation, etc. Synonym: suppurative inflammation. (05 Mar 2000) |
| degenerative inflammation | A local reaction to injury, occasionally observed in the walls of blood vessels and in parenchymal cells of various organs in reacting to certain chemicals, viruses, and other intracellular agents; the response is characterised by degenerative changes in the cytoplasm and nucleus, frequently resulting in necrosis, but exudation (if any) is ordinarily observed only in the wall of the affected vessel, or in the interstices immediately adjacent to the affected vessel or parenchymal cells. Synonym: degenerative inflammation. (05 Mar 2000) |
| immune inflammation | See: allergic reaction. (05 Mar 2000) |
| inflammation | <pathology> A localised protective response elicited by injury or destruction of tissues, which serves to destroy, dilute or wall off (sequester) both the injurious agent and the injured tissue. It is characterised in the acute form by the classical signs of pain (dolor), heat (calor), redness (rubor), swelling (tumour) and loss of function (functio laesa). Histologically, it involves a complex series of events, including dilatation of arterioles, capillaries and venules, with increased permeability and blood flow, exudation of fluids, including plasma proteins and leucocytic migration into the inflammatory focus. Origin: L. Inflammatio, inflammare = to set on fire (11 Jun 1998) |