| hydroxymethylglutaryl-CoA reductase inhibitors | Compounds that inhibit hmg-CoA reductases. They have been shown to directly lower cholesterol synthesis. (12 Dec 1998) |
|---|---|
| neurotransmitter uptake inhibitors | Drugs that inhibit the transport of neurotransmitters into axon terminals or into storage vesicles within terminals. For many transmitters, uptake determines the time course of transmitter action so inhibiting uptake prolongs the activity of the transmitter. Blocking uptake may also deplete available transmitter stores. Many clinically important drugs are uptake inhibitors although the indirect reactions of the brain rather than the acute block of uptake itself is often responsible for the therapeutic effects. (12 Dec 1998) |
| nucleic acid synthesis inhibitors | Compounds that inhibit cell production of DNA or RNA. (12 Dec 1998) |
| dextrin 6-alpha-d-glucosidase | <enzyme> Catalyses endohydrolysis of 1,6-alpha-d-glucoside linkages at points of branching in chains of 1,4-linked alpha-d-glucose residues Registry number: EC 3.2.1.33 (26 Jun 1999) |
| dopamine uptake inhibitors | Drugs that block the transport of dopamine into axon terminals or into storage vesicles within terminals. most of the adrenergic uptake inhibitors also inhibit dopamine uptake. (12 Dec 1998) |
| integrase inhibitors | Compounds which inhibit or antagonise biosynthesis or actions of integrase. (12 Dec 1998) |
| oligo-1,6-glucosidase | <enzyme> An enzyme that catalyses the endohydrolysis of 1,6-alpha-glucosidic linkages in isomaltose and dextrins produced from starch and glycogen by alpha-amylase. Chemical name: Dextrin 6-alpha-D-glucanohydrolase Registry number: EC 3.2.1.10 (12 Dec 1998) |
| oligo-a1,6-glucosidase | A glucanohydrolase cleaving alpha-1,6 links in isomaltose and dextrins produced from starch and glycogen by alpha-amylase; secreted into the duodenum; a deficiency of this enzyme leads to defects in intestinal digestion of limit dextrins. See: sucrose alpha-d-glucohydrolase. Synonym: isomaltase, limit dextrinase. (05 Mar 2000) |
| tissue inhibitors of metalloproteinase | <cell biology> Family of proteins of around 200 residues that can inhibit metalloproteinases, for example collagenase, by binding to them. (18 Nov 1997) |
| enzyme inhibitors | Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (12 Dec 1998) |
| enzymes, coenzymes, and enzyme inhibitors | Proteins or RNA that act as biological catalysts, their cofactors, and inhibitors. (12 Dec 1998) |
| trypsin inhibitors | Serine proteinase inhibitors which inhibit trypsin. They may be endogenous or exogenous compounds. (12 Dec 1998) |
| exo-1,4-alpha-d-glucosidase | A hydrolase removing terminal alpha-1,4-linked d-glucose residues from nonreducing ends of chains, with release of beta-d-glucose. Synonym: acid maltase, amyloglucosidase, gamma-amylase, glucoamylase. (05 Mar 2000) |
| 4-methylumbelliferyl-beta-glucosidase | <enzyme> Aspect of EC 3.2.1.21 Registry number: EC 3.2.1.- (26 Jun 1999) |
| 4-nitrophenyl-alpha-glucosidase | <enzyme> Involved in glycoprotein precessing; cleaves 1-3 linked glucose residues Registry number: EC 3.2.1.- Synonym: pnp-alpha-d-glucosidase, para-nitrophenyl-alpha-glucosidase, glucosidase II (26 Jun 1999) |