| fungal | <microbiology> An infection that is secondary to fungi. Common examples include: tinea versicolour and ringworm. (05 Jan 1998) |
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| fungal arthritis | <pathology, rheumatology> Infection of a joint space by fungus. Common fungi that can cause mycotic arthritis include coccidioidomycosis, histoplasmosis, blastomycosis, cryptococcosis, sporotrichosis and candidiasis. Infection of a joint generally occurs as a result of a primary fungal infection in the lungs. Treatment is with antifungal agents (for example amphotericin B, ketoconazole). (27 Sep 1997) |
| fungal infection | 1. (groin) Tinea cruris is a fungal infection of the perineum, better known as jock itch. This condition is often treated with clotrimazole or miconazole cream. Good general hygiene is vital in the prevention of tinea cruris. Keep the groin area clean and dry and avoid chafing. Launder athletic supporters frequently. Use an antifungal or drying powder after showering. 2. (nail) A fungal infection that involves the fingernails. Nails generally split, flake and grow too thick. 3. (scalp): A fungal scalp infection also known as tinea capitis. A crusting and scaly lesion of the scalp that can also be associated with localised hair loss. Treatment requires oral (systemic) antifungal medications. (05 Jan 1998) |
| fungal nail infection | The most common fungus infection of the nail is onychomycosis. Onychomycosis makes the nails look white and opaque, thickened, and brittle. Older women (perhaps because oestrogen deficiency may increase the risk of infection) and men and women with diabetes or disease of the small blood vessels (peripheral vacscular disease) are at increased risk. Artificial nails (acrylic or wraps ) increase the risk because when an artificial nail is applied, the nail surface is usually abraded with an emery board damaging it, emery boards can carry infection, and water can collect under the nail creating a moist, warm environment for fungal growth. Alternative names include tinea unguium and ringworm of the nails. (12 Dec 1998) |
| fungal proteins | Proteins found in any species of fungus. (12 Dec 1998) |
| fungal vaccines | Suspensions of attenuated or killed fungi administered for the prevention or treatment of infectious fungal disease. (12 Dec 1998) |
| fungal vaginitis | <pathology> A local infection of the vaginal mucosa caused by Candida. (27 Sep 1997) |
| breast cancer susceptibility genes | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. However, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. (12 Dec 1998) |
| cancer, breast, susceptibility genes | Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicised). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre syndrome, and ataxia-telangiectasia) are also known to predispose to breast cancer. However, since all of these known breast cancer susceptibility genes together do not account for more than a minor fraction (1/5th at most) of breast cancer that clusters in families, it is clear that more breast cancer genes remain to be discovered. (12 Dec 1998) |
| genes | Located in the nucleus of the cell, genes contain hereditary information that is transferred from cell to cell. (09 Oct 1997) |
| genes, abl | Retrovirus-associated DNA sequences (abl) originally isolated from the abelson murine leukaemia virus (ab-mulv). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukaemia. (12 Dec 1998) |
| genes, apc | Tumour suppressor genes located in the 5q21 region on the long arm of chromosome 5. The mutation of these genes is associated with familial adenomatous polyposis (apc stands for adenomatous polyposis coli) and gardner's syndrome, as well as some sporadic colourectal cancers. (12 Dec 1998) |
| genes, arac | Regulatory genes which encode a cyclic AMP receptor protein required for l-arabinose utilization in e. Coli. It is an example of positive control or regulation of gene expression in the bacterial operon. (12 Dec 1998) |
| genes, archaeal | The genetic material of archaea. (12 Dec 1998) |
| genes, bacterial | The genetic material of bacteria. (12 Dec 1998) |