| infantile generalised GM1 gangliosidosis | One of the hereditary metabolic diseases of infancy; resembles Tay-Sachs disease, except other organ systems (bone, liver, kidney) are affected. Synonym: familial neuroviscerolipidosis, pseudo-Hurler disease, Type 1 GM1 gangliosidosis. (05 Mar 2000) |
|---|---|
| epilepsy, generalised | Epileptic seizures in which the first clinical changes indicate initial involvement of both hemispheres of the brain, as opposed to epileptic seizures involving a particular focal point of the brain (epilepsy, partial). Generalised seizures can be convulsive or non-convulsive. Consciousness may be impaired and this impairment may be the initial manifestation of the seizure. Motor manifestations, if present, are also bilateral. (12 Dec 1998) |