| primary generalised epilepsy | Epilepsy without evidence of focal or multifocal central nervous system disease. Seizures are generalised from onset, both by EEG and clinical criteria. Often a pure genetic form of epilepsy. See: generalised tonic-clonic seizure. (05 Mar 2000) |
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| secondarily generalised tonic-clonic seizure | A generalised tonic-clonic seizure that begins with a partial seizure and evolves into a generalised tonic-clonic seizure. (05 Mar 2000) |
| secondary generalised epilepsy | A group of epilepsy syndromes of diverse aetiologies with diffuse or multifocal cerebral involvement. Patients typically have a variety of generalised seizure types, including tonic, atonic, myoclonic, atypical absence, and generalised tonic-clonic seizures. Partial seizures may also occur. One classic syndrome is the Lennox-Gastaut syndrome. Synonym: symptomatic epilepsy. (05 Mar 2000) |
| infantile generalised GM1 gangliosidosis | One of the hereditary metabolic diseases of infancy; resembles Tay-Sachs disease, except other organ systems (bone, liver, kidney) are affected. Synonym: familial neuroviscerolipidosis, pseudo-Hurler disease, Type 1 GM1 gangliosidosis. (05 Mar 2000) |
| epilepsy, generalised | Epileptic seizures in which the first clinical changes indicate initial involvement of both hemispheres of the brain, as opposed to epileptic seizures involving a particular focal point of the brain (epilepsy, partial). Generalised seizures can be convulsive or non-convulsive. Consciousness may be impaired and this impairment may be the initial manifestation of the seizure. Motor manifestations, if present, are also bilateral. (12 Dec 1998) |