| gene fusion | Fusion of structural genes to analyze protein behaviour or fusion of regulatory sequences with structural genes to determine mechanisms of regulation. (12 Dec 1998) |
|---|---|
| gene insertion | The addition of one or more genesinto a genome from an externalsource. (09 Oct 1997) |
| gene isolation | A condition caused by a pair of alleles that, when present in the heterozygous form, inhibit the fertility of the organism that possessesthem. (09 Oct 1997) |
| gene library | <molecular biology> A collection of cloned DNA fragments that contains all the genetic information of a particular organism. (09 Oct 1997) |
| gene machine | A computerised device for synthesizing genes by combining nucleotides (bases) in a specified order. (14 Nov 1997) |
| gene mapping | Determination of the relative positions of genes on a DNA molecule (chromosome or plasmid) and of the distance, in linkage units or physical units, between them. (09 Oct 1997) |
| gene markers | Detectable genetic traits or distinctive segments of DNA that serve as landmarks for a target gene. Markers are on the same chromosome as the target gene. They must be near enough to the target gene to be genetically linked to it: to be inherited usually together with that gene, and so serve as signposts to it. (12 Dec 1998) |
| gene mosaicism | <genetics> Descriptive of an organism that consists of two or more genetically distinct cell lines. (14 Nov 1997) |
| gene pool | The total sum of genetic information present in a population at anygiven moment. (09 Oct 1997) |
| gene probe | A biomolecule that islabelled with radioactive isotopes or with a fluorescent marker that selectively binds to a specific gene so it can be isolated or identified. (09 Oct 1997) |
| gene product | The biochemical material, either RNA or protein, resulting from expression of a gene. The amount of gene product is used to measure how active a gene is, abnormal amounts can be correlated with disease-causing alleles. (09 Oct 1997) |
| gene products, env | Retroviral proteins, often glycosylated, coded by the envelope (env) gene. They are usually synthesised as protein precursors (polyproteins) and later cleaved into the final products by a viral protease. (12 Dec 1998) |
| gene products, gag | Proteins coded by the retroviral gag gene. The products are usually synthesised as protein precursors or polyproteins, which are then cleaved by viral proteases to yield the final products. Many of the final products are associated with the nucleoprotein core of the virion. Gag is short for group-specific antigen. (12 Dec 1998) |
| gene products, nef | Products of the HIV nef gene (formerly 3'-orf gene). The products trans-suppress viral replication and function as negative regulators of transcription. Nef stands for negative factor. (12 Dec 1998) |
| gene products, pol | Retroviral proteins coded by the pol gene. Often synthesised as a gag-pol fusion protein (fusion proteins, gag-pol) and later cleaved into final products that include reverse transcriptase, endonuclease/integrase, and viral protease. Pol is short for polymerase, the enzyme class of reverse transcriptase. (12 Dec 1998) |
| reporter gene | <molecular biology> A gene that encodes an easily assayed product (e.g. CAT) that is coupled to the upstream sequence of another gene and transfected into cells. The reporter gene can then be used to see which factors activate response elements in the upstream region of the gene of interest. (18 Nov 1997) |
|---|---|
| repressor gene | A gene that prevents a nonallele from being transcribed. (05 Mar 2000) |
| C gene | The gene coding for the constant regions of immunoglobulin chains. (05 Mar 2000) |
| rho gene | <molecular biology> Genes coding for small GTP-binding proteins, implicated in actin organisation and the interaction of the cytoskelton with intracellular membranes. See: ras, rab. (23 Aug 1998) |
| chloramphenicol acetyltransferase gene | <molecular biology> A gene which codes for the CAT enzyme (the enzyme chloramphenicol acetyltransferase), which helps transfer an acetyl group (a CH3CO- group) to chloramphenicol, an antibiotic. The CAT gene is an important part of CAT assays. (09 Oct 1997) |
| mitochondrial gene | A functioning gene located not in the nucleus of a cell but in the mitochondrial chromosome. (05 Mar 2000) |
| modifier gene | A nonallelic gene that controls or changes the manifestation of a gene by interfering with its transcription. (05 Mar 2000) |
| codominant gene | A set of two or more alleles, each expressed phenotypically in the presence of the other. (05 Mar 2000) |
| pleiotropic gene | A gene that has multiple, apparently unrelated, phenotypic manifestations. Synonym: polyphenic gene. (05 Mar 2000) |
| constitutive gene | A gene which is continuously expressed without any regulation (transcription can be neither suppressed nor encouraged). These genes generally encode housekeeping functions and are expressed at low levels in all cells. (09 Oct 1997) |
| control gene | See: operator gene, regulator gene. (05 Mar 2000) |
| pol gene | <molecular biology> Genes coding for DNA polymerases of which there are three in E. Coli, polA, polB and polC coding for polymerases I, II and III respectively. Pol genes in oncogenic retroviruses code for reverse transcriptase. (18 Nov 1997) |
| mutant gene | A gene that has been changed from an ancestral type, not necessarily in the current generation. See: mutant, mutation. (05 Mar 2000) |
| polyphenic gene | A gene that has multiple, apparently unrelated, phenotypic manifestations. Synonym: polyphenic gene. (05 Mar 2000) |
| cytoplasmic gene | <molecular biology> A gene which occurs outside the nucleus of an eukaryote or outside the regular chromosomes of a bacteria. (09 Oct 1997) |
Synonyms : Regulation, Gene Expression, Bacterial
Synonyms : Regulation, Gene Expression, Developmental, Regulation, Gene Expression, Embryologic
Synonyms : Regulation, Gene Expression, Enzymologic
Synonyms : Regulation, Gene Expression, Fungal
Synonyms : Regulation, Gene Expression, Leukemic
| genetic map |
graphical representation of the arrangement of genes on a chromosome
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| general anesthesia |
a state of total unconsciousness resulting from anesthetic drugs (as for a major surgical operation)
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| genetic engineering |
the technology of preparing recombinant DNA in vitro by cutting up DNA molecules and splicing together fragments from more than one organism
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| general anatomy |
anatomy: the branch of morphology that deals with the structure of animals
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| generalization |
abstraction: the process of formulating general concepts by abstracting common properties of instances reasoning from detailed facts to general principles an idea or conclusion having general application; "he spoke in broad generalities" (psychology) transfer of a response learned to one stimulus to a similar stimulus
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| gene | somewhat indefinite |
|---|---|
| gene | an agent who sells insurance |
| gene | someone authorized to transact every kind of business for the principal |
| gene | agreement of the majority in sentiment or belief |
| gene | a United Nations agency created by a multinational treaty to promote trade by the reduction of tariffs and import quotas |
| gene | a state of total unconsciousness resulting from anesthetic drugs (as for a major surgical operation) |
| gene | an anesthetic that anesthetizes entire body and causes loss of consciousness |
| gene | a state of total unconsciousness resulting from anesthetic drugs (as for a major surgical operation) |
| gene | an anesthetic that anesthetizes entire body and causes loss of consciousness |
| gene | persons who make or amend or repeal laws |
| gene | the supreme deliberative assembly of the United Nations |
| gene | group of Baptist congregations believing the teachings of the Dutch theologian Jacobus Arminius (who opposed the doctrine of strict predestination of the Calvinists) |
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