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gamma emission <physics> Nuclear decay process whereby the nucleus goes from an excited state to a more stable state by emitting a gamma ray.
See: gamma ray.
(09 Oct 1997)
gamma encephalography Imaging of the encephalon by the administration of small amounts of gamma-emitting radionuclides; commonly called a brain scan; superseded by computed tomography and magnetic resonance imaging.
(05 Mar 2000)
gamma-endorphin <chemical> An endogenous opioid peptide derived from the pro-opiomelanocortin precursor peptide. It differs from alpha-endorphin by one amino acid.
Chemical name: gamma-Endorphin
(12 Dec 1998)
gamma fibres Nerve fibre's that have a conduction rate of about 20 m/sec.
See: gamma efferent.
(05 Mar 2000)
gamma globulin <immunology> A non-specific immunoglobulin (antibody) administered for the purpose of passive immunity. A common example is hepatitis A prophylaxis.
(27 Sep 1997)
gamma-globulins Serum globulins that migrate in the gamma region on electrophoresis. At one time, gamma-globulins came to be used as a synonym for immunoglobulins since most immunoglobulins are gamma globulins. But since some immunoglobulins exhibit an alpha or beta electrophoretic mobility, that usage is in decline.
(12 Dec 1998)
gamma-glutamyl carboxylase <enzyme> An enzyme that catalyses the formation of gamma-carboxyglutamyl residues in many proteins, several appearing in the blood clotting cascade.
(05 Mar 2000)
gamma-glutamyl cycle A proposed pathway for the glutathione-dependent transport of certain amino acids (most notably l-cystine, l-methionine, and l-glutamine) and dipeptides into certain cells; this cycle requires the formation of gamma-glutamyl amino acids and gamma-glutamyl dipeptides as well as a protein for the translocation of these di-and triisopeptides into the cells.
(05 Mar 2000)
gamma-glutamylcyclotransferase <enzyme> An enzyme that catalyses the synthesis of pyroglutamate from a gamma-glutamyl-amino acid, also releasing the free amino acid. The enzyme acts on derivatives of glutamate, 2-aminobutyrate, alanine and glycine. The enzyme has been proposed to have a role in a gamma-glutamyl cycle for amino acid transport into cells in the intestines.
Chemical name: (5-L-Glutamyl)-L-amino-acid 5-glutamyltransferase (cyclizing)
Registry number: EC 2.3.2.4
(12 Dec 1998)
gamma-glutamylcysteine A necessary precursor in the biosynthesis of glutathione; contains an isopeptide rather than a eupeptide bond.
Gamma-glutamylcysteine synthetase, an enzyme that catalyses the first step in glutathione biosynthesis, reacting l-glutamate, l-cysteine, and ATP to form gamma-glutamylcysteine, ADP, and orthophosphate; inhibited by thiols such as glutathione.
(05 Mar 2000)
gamma-glutamyl dipeptidase <enzyme> Removes glycine from leukotriene d4 to form leukotriene e4
Registry number: EC 3.4.13.-
(26 Jun 1999)
gamma-glutamylhistamine synthetase <enzyme> Incorporates histamine or other amines into peptide linkage with glutamate; from aplysia ganglia
Registry number: EC 6.3.2.-
Synonym: gamma-gha synthetase, gamma-glutamyl amine synthetase, gamma-glutamyl octopamine synthetase, gamma-glutamyl tyramine synthetase
(26 Jun 1999)
gamma-glutamyl hydrolase N-Pteroyl-l-glutamate hydrolase;an enzyme cleaving l-glutamyl residues from pteridine oligoglutamates; used in certain antitumour treatments.
Synonym: carboxypeptidase G, conjugase, gamma-glutamate (glutamate gamma-) carboxypeptidase.
(05 Mar 2000)
gamma-glutamyltransferase <enzyme> An enzyme that catalyses reversibly the transfer of a glutamyl group from a glutamyl-peptide and an amino acid to a peptide and a glutamyl-amino acid. It is often elevated above normal in hepatitis and other conditions that cause chemical liver damage.
Chemical name: (5-L-Glutamyl)-peptide:amino-acid 5-glutamyltransferase
Registry number: EC 2.3.2.2
Acronym: GGT
(12 Sep 2002)
gamma-glutamyl transpeptidase <enzyme> An enzyme that catalyses reversibly the transfer of a glutamyl group from a glutamyl-peptide and an amino acid to a peptide and a glutamyl-amino acid. It is often elevated above normal in hepatitis and other conditions that cause chemical liver damage.
Chemical name: (5-L-Glutamyl)-peptide:amino-acid 5-glutamyltransferase
Registry number: EC 2.3.2.2
Acronym: GGT
(12 Sep 2002)
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