| FDP | fibrin degradation product; fibrinogen degradation product; flexor digitorum profundus; frontodextra... |
|---|---|
| FDPase | fructose-1,6-diphosphatase |
| FMP | faculty mentorship program; first menstrual period; fructose monophosphate |
| F1P, | F-1-P fructose-1-phosphate |
| F6P, | F-6-P fructose-6-phosphate |
| 6-phosphofructo-2-kinase-fructose-2,6-bisphosphatase | <chemical> Hepatic bifunctional enzyme that both degrades and synthesises fructose-2,6-bisphosphate Synonym: 6pf-2-k-fru-2,6-p(2)ase, hepatic 6-phosphofructo-2-kinase, hepatic fructose-2,6-bisphosphatase, pfk-2 (liver), pbpase-2 (liver) (26 Jun 1999) |
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| fructose | <biochemistry> A 6 carbon sugar (hexose) abundant in plants. Fructose has its reducing group (carbonyl) at C2 and thus is a ketose, in contrast to glucose that has its carbonyl at C1 and thus an aldose. Sucrose, common table sugar, is the nonreducing disaccharide formed by an alpha linkage from C1 of glucose to C2 of fructose (latter in furanose form). Fructose is a component of polysaccharides such as inulin, levan. (18 Nov 1997) |
| fructose 1,6-bisphosphate | <biochemistry> This key intermediate in glycolysis and gluconeogenesis (a hexose diphosphate) was discovered by Arthur Harden and William Young in 1905. In the third step of glycolysis, fructose 6-phosphate and ATP are converted to fructose 1,6-bisphosphate and ADP with the aid of phosphofructokinase. In step 4, fructose 1,6 bisphosphate (with the aid of aldolase) is cleaved into duhydroxyacetone phosphate and glyceraldehyde 3-phosphate. Synonym: hexosebisphosphatase, hexosediphosphatase. (08 Mar 2000) |
| fructose-1,6-diphosphatase deficiency | An autosomal recessive fructose metabolism disorder due to absent or deficient fructose-1,6-diphosphatase activity. Gluconeogenesis is impaired, resulting in accumulation of gluconeogenic precursors (e.g., amino acids, lactate, ketones) and manifested as hypoglycaemia, ketosis, and lactic acidosis. Episodes in the newborn infant are often lethal. Later episodes are often brought on by fasting and febrile infections. As patients age through early childhood, tolerance to fasting improves and development becomes normal. (12 Dec 1998) |
| fructose-1,6-diphosphate reductase | <enzyme> From bovine lens; reduces fructose-1,6-diphosphate to sorbitol-1,6-diphosphate in presence of NADH; 3 isoenzymes which copurify with lactate dehydrogenase isoenzymes Registry number: EC 1.1.1.- Synonym: fdp reductase (26 Jun 1999) |
| fructose 1-phosphate | A fructose derivative that accumulates in individuals with hereditary fructose intolerance. (05 Mar 2000) |
| fructose 2,6-bisphosphate | An analog of fructose 1,6-bisphosphate that plays a key role in the regulation of glycolysis and gluconeogenesis; activates phosphofructokinase and inhibits fructose 1,6-bisphosphatase. (05 Mar 2000) |
| fructose-2,6-bisphosphate 2-phosphatase | <enzyme> Copurifies with 6-phosphofructo-2-kinase; probably is a single protein with both activities; do not confuse with EC 3.1.3.54, fructose-2,6-bisphosphate 6-phosphatase Registry number: EC 3.1.3.46 Synonym: fructose-2,6-diphosphatase, fructose 2,6-bisphosphatase, fructose-2,6-bisphosphatase (26 Jun 1999) |
| fructose-2,6-bisphosphate 6-phosphatase | <enzyme> Do not confuse with fructose-2,6-bisphosphate 2-phosphatase (EC 3.1.3.46) Registry number: EC 3.1.3.54 Synonym: fdp 6-phosphatase, fru(2,6)p2 6-phosphatase (26 Jun 1999) |
| fructose 6-phosphate | <biochemistry> A phosphorylated six-carbon sugar formed in the second step of glycolysis by the action of phosphoglucose isomerase on glucose-6-phosphate. In the third step, fructose 6-phospate and ATP are used to create fructose 1,6-biphosphate, ADP and a free hydrogen with the aid of phosphofructokinase. (08 Mar 2000) |
| fructose-6-phosphate phosphoketolase | <enzyme> Catalyses the conversion of d-fructose 6-phosphate and orthophosphate to acetylphosphate and d-erythrose 4-phosphate and water Registry number: EC 4.1.2.22 Synonym: f6p phosphoketolase (26 Jun 1999) |
| fructose-bisphosphatase | <enzyme> An enzyme that catalyses the conversion of d-fructose 1,6-bisphosphate and water to d-fructose 6-phosphate and orthophosphate. Chemical name: D-Fructose-1,6-bisphosphate 1-phosphohydrolase Registry number: EC 3.1.3.11 (12 Dec 1998) |
| fructose intolerance | An autosomal recessive fructose metabolism disorder due to deficient fructose-1-phosphate aldolase (ec 2.1.2.13) activity, resulting in accumulation of fructose-1-phosphate. The accumulated fructose-1-phosphate inhibits glycogenolysis and gluconeogenesis, causing severe hypoglycaemia following ingestion of fructose. Prolonged fructose ingestion in infants leads ultimately to hepatic failure and death. Patients develop a strong distaste for sweet food, and avoid a chronic course of the disease by remaining on a fructose- and sucrose-free diet. (12 Dec 1998) |
| fructose metabolism, inborn errors | Inherited abnormalities of fructose metabolism, which include three known autosomal recessive types: hepatic fructokinase deficiency (essential fructosuria), hereditary fructose intolerance, and hereditary fructose-1,6-diphosphatase deficiency. Essential fructosuria is a benign asymptomatic metabolic disorder caused by deficiency in fructokinase, leading to decreased conversion of fructose to fructose-1-phosphate and alimentary hyperfructosaemia, but with no clinical dysfunction; may produce a false-positive diabetes test. (12 Dec 1998) |
| fructose permease | <chemical> Fructose-specific enzyme II of phosphoenolpyruvate-dependent phosphotransferase system in e. Coli (26 Jun 1999) |