| Frank, Otto | <person> German physiologist, 1865-1944. See: Frank-Starling curve. (05 Mar 2000) |
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| Frank-Starling curve | A graph in which cardiac output or stroke volume is plotted against mean atrial or ventricular end-diastolic pressure; with increasing venous return and atrial pressure the output proportionately increases until further increments overload the heart and the output falls. Synonym: Frank-Starling curve. (05 Mar 2000) |