| granuloma | <pathology> Chronic inflammatory lesion characterised by large numbers of cells of various types (macrophages, lymphocytes, fibroblasts, giant cells), some degrading and some repairing the tissues. (18 Nov 1997) |
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| granuloma annulare | <dermatology> Benign granulomatous disease of unknown aetiology characterised by a ring of localised or disseminated papules or nodules on the skin and palisading histiocytes surrounding necrobiotic tissue resulting from altered collagen structures. (12 Dec 1998) |
| granuloma endemicum | <dermatology, infectious disease> The lesion occurring in cutaneous leishmaniasis. (05 Mar 2000) |
| granuloma faciale | <dermatology> Persistent well-demarcated nodules that usually appear on the face and consist of a dense dermal infiltrate of eosinophils and neutrophils, separated from the epidermis and hair follicles, with fibrinoid vasculitis. (05 Mar 2000) |
| granuloma, fish bowl | Localised nodular skin inflammation (small reddish raised areas of skin) caused by a bacterium called mycobacterium marinum. Fish bowl granuloma is typically acquired by occupational or recreational exposure to salt or fresh water, often resulting from minor trauma during caring for aquariums. The diagnosis is suggested by the history of exposure and confirmed by culturing tissue specimens which yield the microscopic organism, mycobacterium marinum. The infection can be treated with a variety of antibiotics, including doxycycline, minocycline, clarithromycin, rifampin, and trimethoprim-sulfamethoxazole. Also called swimming pool granuloma. (12 Dec 1998) |
| granuloma gangrenescens | Destruction of the nasal septum, hard palate, lateral nasal walls, paranasal sinuses, skin of the face, orbit and nasopharynx by an inflammatory infiltrate with atypical lymphocytic and histiocytic cells; presumably a form of lymphoma in most cases. An obsolete term for polymorphic reticulosis. Synonym: granuloma gangrenescens, malignant granuloma, midline malignant reticulosis granuloma. (05 Mar 2000) |
| granuloma gravidarum | A pyogenic granuloma developing on the gingiva during pregnancy; thought to be related to hormonally altered response of the oral mucous membranes to local irritants such as bacterial plaque on adjacent teeth. Synonym: pregnancy tumour. (05 Mar 2000) |
| granuloma inguinale | <disease, microbiology> A rare sexually transmitted disease that is caused by Calymmatobacterium granulomatis. This infection is more common in the tropical and subtropical areas such as India, Guyana and new Guinea. There are approximately 100 cases reported annually in the United States. Men are affected more often than women. It is thought to be most commonly acquired through anal intercourse. Symptoms include a small red nodule on the genitalia that may form elevated masses of reddened tissue (granulation tissue). The lesions gradual spread and destroy genital tissue. Diagnosis is via tissue biopsy or culture. Treatment includes antibiotics. (27 Sep 1997) |
| granuloma inguinale tropicum | An elongated ulcer, with elevated papillary edges, sometimes occurring in the groin in persons in the tropics. Synonym: groin ulcer. (05 Mar 2000) |
| granuloma, laryngeal | A polypoid granulomatous projection into the lumen of the larynx. (12 Dec 1998) |
| granuloma, lethal midline | A non-neoplastic disease of unknown aetiology beginning with inflammation, ulceration, and perforation of nose and palate and progressing to gradual destruction of midline facial structures. (12 Dec 1998) |
| granuloma multiforme | A chronic granulomatous annular eruption of the skin on the upper body in older adults in central Africa; of unknown cause. (05 Mar 2000) |
| granuloma, plasma cell | A slow-growing benign pseudotumour in which plasma cells greatly outnumber the inflammatory cells. (12 Dec 1998) |
| granuloma, plasma cell, orbital | A distinctive, chronic inflammatory reaction in the orbital tissues of the eye, of unknown aetiology, that may closely resemble a neoplasm and often becomes bilateral. Symptoms include exophthalmos and congestion of the lids with oedema. When limitation of ocular motility also occurs, it is sometimes called orbital myositis. (12 Dec 1998) |
| granuloma, plasma cell, pulmonary | A pseudotumour of the lung composed of inflammatory cells and showing complete maturity of fibroblastic components with a striking lack of mitosis. It is also called postinflammatory pseudotumour and pseudoneoplastic pneumonitis. (berardi, r.s. Et al. Inflammatory pseudotumours of the lung. Surg gynecol obstet 156:89-96, jan 83) (12 Dec 1998) |