| nabothian follicle | <radiology> Chronic cervicitis most likely to be inflammatory stenosis of cervical glands most likely to be retention most likely to be cyst Differential diagnosis: cystic mass of cervix, ectopic pregnancy, adenomyosis (12 Dec 1998) |
|---|---|
| neck of hair follicle | The narrowed part of the hair follicle between the hair bulb and the surface of the skin. Synonym: collum folliculi pili. (05 Mar 2000) |
| dental follicle | <dentistry> The dental sac with its enclosed odontogenic organ and developing tooth. (05 Mar 2000) |
| ovarian follicle | <biology, gynaecology> In mammals the group of cells around the primary oocyte proliferate and form a surrounding noncellular layer. A space opens up in the follicle cells and the whole structure is then the ovarian Graafian) follicle. (05 Jan 1998) |
| follicle | 1. <anatomy> Generally a small sac or vesicle. 2. <botany> A kind of fruit formed from a single carpel, that splits to release its seeds. 3. <dermatology> A hair follicle, an invagination of the epidermis into the dermis surrounding the hair root. 4. <gynaecology, physiology> An ovarian follicle, an oocyte surrounded by one or more layers of granulosa cells. As the ovarian follicle develops a cavity forms and it is then termed a Graafian follicle. (12 Nov 1997) |
| follicle cell | <gynaecology, pathology> A layer of cells within an ovarian follicle which surrounds the oocyte (proto-ovum) and provides certain nutrients to it. (09 Oct 1997) |
| luteinised unruptured follicle syndrome | <syndrome> The failure of a follicle to release the egg even though a corpus luteum has formed. (09 Oct 1997) |
| lymph follicle | Lymphatic follicle, one of the spherical masses of lymphoid cells, frequently having a more lightly staining centre. See: solitary lymphatic follicles, Peyer's patches. Synonym: folliculus lymphaticus, lymph nodule, nodulus lymphaticus. (05 Mar 2000) |
| macrophage colony-stimulating factor | <growth factor> A glycoprotein growth factor that causes the committed cell line to proliferate and mature into macrophages. A cytokine synthesised by mesenchymal cells that stimulates pluripotent stem cells of bone marrow into differentiating towards the production of monocytes (mononuclear phagocytes). The compound stimulates the survival, proliferation, and differentiation of haematopoietic cells of the monocyte-macrophage series. It is a disulfide-bonded glycoprotein dimer with a mw of 70 kD and binds to a single class of high affinity receptor which is identical to the product of the c-fms proto-oncogene. See: colony-stimulating factors. Chemical name: Colony-stimulating factor 1 Acronym: M-CSF (12 Dec 1998) |
| receptors, colony-stimulating factor | Cell surface receptors for colony-stimulating factors, local mediators, and hormones that regulate the survival, proliferation, and differentiation of haemopoietic cells. (12 Dec 1998) |
| receptors, granulocyte-colony-stimulating factor | Receptors that bind and internalise granulocyte-colony-stimulating factor. Their mw is believed to be 150 kD. These receptors are found mainly on a subset of myelomonocytic cells. (12 Dec 1998) |
| receptors, granulocyte-macrophage colony-stimulating factor | Receptors that bind and internalise the granulocyte-macrophage stimulating factor. Their mw is believed to be 84 kD. The most mature myelomonocytic cells, specifically human neutrophils, macrophages, and eosinophils, express the highest number of affinity receptors for this growth factor. (12 Dec 1998) |
| receptors, macrophage colony-stimulating factor | Glycoproteins of mw 165 kD which are encoded by the c-fms proto-oncogene. The binding of csf-1 to its receptors activates an intrinsic tyrosine kinase activity resulting in autophosphorylation of the receptors on tyrosine, rapid receptor down-regulation, and phosphorylation of as yet unidentified physiologic substrates that initiate a mitogenic response. (12 Dec 1998) |
| granulocyte-colony-stimulating factor | <growth factor, haematology, oncology> A glycoprotein of 25 kD containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukaemic myeloid cell lines. A protein that stimulates the growth and maturation of granulocytes. It is used to promote the recovery of the white cells following chemotherapy. See: colony-stimulating factor. Acronym: G-CSF (12 Dec 1998) |
| granulocyte-macrophage colony-stimulating factor | <growth factor, haematology, oncology> An acidic glycoprotein of mw 23 kD with internal disulfide bonds. It is produced in response to a number of inflammatory mediators by mesenchymal cells present in the haemopoietic environment and at peripheral sites of inflammation. It stimulates the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from foetal liver progenitor cells. It also has some functional activities in mature granulocytes and macrophages. It is used to promote the recovery of the white blood cells following chemotherapy. Chemical name: Colony-stimulating factor 2 See: colony-stimulating factor. Acronym: GM-CSF (12 Dec 1998) |