| inflammation | <pathology> A localised protective response elicited by injury or destruction of tissues, which serves to destroy, dilute or wall off (sequester) both the injurious agent and the injured tissue. It is characterised in the acute form by the classical signs of pain (dolor), heat (calor), redness (rubor), swelling (tumour) and loss of function (functio laesa). Histologically, it involves a complex series of events, including dilatation of arterioles, capillaries and venules, with increased permeability and blood flow, exudation of fluids, including plasma proteins and leucocytic migration into the inflammatory focus. Origin: L. Inflammatio, inflammare = to set on fire (11 Jun 1998) |
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| inflammation: gallium imaging | <radiology> Pathophysiology: leakage of protein-bound Ga-67 into extracellular space secondary to increased capillary permeability, Ga-67 is preferentially bound to nonviable PMNs and macrophages, leukocyte incorporation (rich in lactoferrin), bacterial uptake (siderophores), inflammtory tissue stimulates lactoferrin production for chronic abdominal inflammation: 67% sensitivity; 64% specificity; 13% false negatives; 5% false positive, dose: 5 mCi; imaging: 24, 48, 72 hours, diffuse uptake in peritonitis, localised uptake in acute pyogenic abscess, phlegmon, acute cholecystitis, acute pancreatitis, acute gastritis, diverticulitis, inflammatory bowel disease, surgical wound, pyelonephritis, perinephric abscess see: gallium indications, gallium vs. Indium (12 Dec 1998) |
| inflammation mediators | The endogenous compounds that mediate inflammation (autacoids) and related exogenous compounds including the synthetic prostaglandins (prostaglandins, synthetic). (12 Dec 1998) |
| interstitial inflammation | Inflammation in which the inflammatory reaction occurs chiefly in the supportive fibrous connective tissue or stroma of an organ. (05 Mar 2000) |
| exudative inflammation | Inflammation in which the conspicuous or distinguishing feature is an exudate, which may be chiefly serous, serofibrinous, fibrinous, or mucous (e.g., relatively few cells are present), or may be characterised by relatively large numbers of neutrophils, eosinophils, lymphocytes, monocytes, or plasma cells, frequently with one or two types being predominant; it occurs not only as a separate and distinct pathologic process, but also frequently as a part of certain granulomatous inflammation's. (05 Mar 2000) |
| fibrinopurulent inflammation | A purulent inflammation in which the exudate contains an unusually large amount of fibrin; also, a fibrinous or serofibrinous inflammation in which the accumulation of large numbers of polymorphonuclear leukocytes results in liquefactive necrosis of tissue and the formation of pus with a relatively large quantity of fibrin. (05 Mar 2000) |
| fibrinous inflammation | An exudative inflammation in which there is a disproportionately large amount of fibrin. (05 Mar 2000) |