| nodular fasciitis | A rapidly-growing tumour-like proliferation of fibroblasts, not thought to be neoplastic, with mild inflammatory exudation occurring in fascia; the fibrosis may infiltrate surrounding tissue but does not progress indefinitely or metastasize. Synonym: pseudosarcomatous fasciitis. (05 Mar 2000) |
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| nodular headache | Radiating pain in the head accompanied by nodular swellings in the splenius, frontalis, trapezius, and other muscles. (05 Mar 2000) |
| nodular hidradenoma | <tumour> A tumour derived from eccrine sweat glands, composed of glycogen-rich clear cells. Synonym: eccrine acrospiroma, nodular hidradenoma. (05 Mar 2000) |
| nodular histiocytic lymphoma | <tumour> A B-cell lymphoma with nodular or diffuse lymph node or bone marrow involvement by large lymphoid cells. Synonym: follicular predominantly small cleaved cell lymphoma, nodular histiocytic lymphoma. (05 Mar 2000) |
| nodular hyperplasia of prostate | Glandular and stromal hyperplasia occurring very commonly in the middle and lateral lobes of older men, forming nodules that may increasingly obstruct the urethra. Synonym: benign prostatic hypertrophy. (05 Mar 2000) |
| nodular iritis | Iritis with aggregations of round cells in the iris. (05 Mar 2000) |
| nodular leprosy | A benign, stable, and resistant form of the disease in which the lepromin reaction is strongly positive and in which the lesions are erythematous, insensitive, infiltrated plaques with clear-cut edges. Synonym: nodular leprosy, smooth leprosy. (05 Mar 2000) |
| nodular lymphoma | <tumour> A malignant lymphoma arising from lymphoid follicular B-cells which may be small or large, growing in a nodular pattern. Synonym: follicular lymphoma, giant follicular lymphoblastoma. (05 Mar 2000) |
| nodular melanoma | <tumour> Primary cutaneous melanoma characterised by dermal invasion extending to the lateral margins of epidermal involvement or ulceration. (05 Mar 2000) |
| nodular non-X histiocytosis | A rare recurring generalised eruption in adults of flesh coloured or erythematous papules remaining localised to the skin and consisting of dermal nodules of mononuclear histiocytes that do not stain for lipid. Synonym: nodular non-X histiocytosis. (05 Mar 2000) |
| nodular opacity | A solitary, round, circumscribed shadow found in the lung on chest radiograph; causes include granuloma, primary or metastatic carcinoma, benign tumour, vascular malformation. Synonym: coin lesion of lungs. (05 Mar 2000) |
| nodular regenerative hyperplasia | A rare condition in which nodules of hyperplastic hepatocytes develop without fibrosis or general loss of lobular architecture. Synonym: nodular regenerative hyperplasia. (05 Mar 2000) |
| nodular scleritis | Firm, immobile, single or multiple areas of localised scleritis. (05 Mar 2000) |
| nodular sclerosis | <cardiology, pathology> The progressive narrowing and hardening of the arteries over time. This is known to occur to some degree with aging, but other risk factors that accelerate this process have been identified. These factors include: high cholesterol, high blood pressure, smoking, diabetes and family history for atherosclerotic disease. (27 Sep 1997) |
| nodular subepidermal fibrosis | A slowly growing benign skin nodule consisting of poorly demarcated cellular fibrous tissue enclosing collapsed capillaries with scattered haemosiderin-pigmented and lipid macrophages. They are common, usually about 1 cm in diameter and occur in the dermis. Simple excision is always curative. (12 Dec 1998) |