| ergot alkaloid-associated heart disease | Heart disease caused by endomyocardial fibrosis which extends into valve structures, producing stenosis and/or regurgitation, associated with ergot alkaloid use. (05 Mar 2000) |
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| ergot alkaloids | Alkaloids isolated from the ergot fungus claviceps purpurea (hypocreaceae). The ergot alkaloids were the first alpha-adrenergic antagonists discovered, but side effects generally prevent their administration in doses that would produce more than a minimal blockade in humans. Their smooth muscle-stimulating activities may be attributed to alpha-agonistic properties, thus characterizing these alkaloids as a series of partial agonists. They have many clinical applications, notably in obstetrics and the treatment of migraine. (12 Dec 1998) |
| ergot poisoning | A syndrome brought on by the consumption of bread (notably rye) contaminated by the ergot fungus, Claviceps purpurea (rye smut), the source of numerous ergot alkaloids. The effects observed include peripheral vascular constriction leading to gangrene, partial paralysis with numbing, tingling and burning in the limbs, feeble pulse, restlessness, stupor or delirium. Can prove fatal. (05 Mar 2000) |
| ergotamine | <chemical> A vasoconstrictor found in ergot of central europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine headaches. Pharmacological action: adrenergic alpha-agonists, analgesics, non-narcotic, vasoconstrictor agents. Chemical name: Ergotaman-3',6',18-trione, 12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'alpha)- (12 Dec 1998) |
| ergotamine derivatives | Analogs and derivatives of ergotamine. (12 Dec 1998) |
| ergotaminine | An isomer of ergotamine but practically inert. (05 Mar 2000) |
| ergotherapy | Treatment of disease by muscular exercise. Origin: G. Ergon, work, + therapeia, therapy (05 Mar 2000) |
| ergothioneine | <chemical> Chemical name: 1H-Imidazole-4-ethanaminium, alpha-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-, inner salt, (S)- (12 Dec 1998) |
| ergotic | Pertaining to, or derived from, ergot; as, ergotic acid. Source: Websters Dictionary (01 Mar 1998) |
| ergotin | <medicine> An extract made from ergot. Source: Websters Dictionary (01 Mar 1998) |
| ergotine | <chemistry> A powerful astringent alkaloid extracted from ergot as a brown, amorphous, bitter substance. It is used to produce contraction of the uterus. Source: Websters Dictionary (01 Mar 1998) |
| ergotism | Chronic poisoning from excessive or misdirected use of ergot as a medicine or from eating ergotised grain, it is marked by cerebrospinal symptoms, spasms and cramps or by a kind of dry gangrene. Synonym: St. Anthony's Fire. (18 Nov 1997) |
| ergotized | Affected with the ergot fungus; as, ergotized rye. Source: Websters Dictionary (01 Mar 1998) |
| ergotoxine | A mixture of alkaloids obtained from ergot, consisting of 1:1:1 ergocristine, ergocornine and ergocryptine, more toxic than other natural and semisynthetic ergot alkaloids; a potent stimulant of smooth muscle, particularly of the blood vessels and uterus, and produces adrenergic blockade (chiefly of the alpha receptors). Synonym: ecboline. (05 Mar 2000) |
| ergotropic | The term introduced by W.R. Hess to denote those mechanisms and the functional status of the nervous system that favour the organism's capacity to expend energy, as distinguished from the trophotropic mechanisms promoting rest and reconstitution of energy stores. In general, the balance between ergotropic and trophotropic nervous mechanisms corresponds in large part to that between the sympathetic and parasympathetic subdivisions of the autonomic nervous system. Origin: ergo-+ G. Tropos, a turning (05 Mar 2000) |