| 영문 | antianginal drug | 한글 | 항협심증제 |
|---|---|---|---|
| 설명 | 협심증은 심장동맥의 혈류를 좋게하거나 심장이 혈류에 비해서 많은 일을 하는 것을 억제함으로써 치료될 수 있다. ① nitrate계통의 약물: 혈관을 이완시키는 작용을 함으로써 심장동맥의 혈류를 좋게 한다. ② 칼슘통로차단제(verapamil, nifedipine): 모든 근육의 수축에는 Ca이 관여한다. 즉 Ca이 있어야만 근육의 수축이 가능해진다. 그러므로 Ca이 세포속으로 들어가는 것을 억제하는 약제는 근육의 수축을 막는다. 이 약은 심장의 근육에 작용하여 심장 근육의 수축을 억제하며 심장이 과도하게 일하는 것을 막고, 또 심장동맥의 수축에 관여하는 근육에 작용을 하여 심장동맥을 이완시켜서 혈류를 좋게 한다. ③ 베타차단제(beta-blocker): 신체의 운동량이나 기타의 요구에 의해서 심장을 빨리 뛰게하는 신경은 바로 베타-교감신경이다. 교감신경계란 사람이 위급한 상황에서 작용하는 자율신경계이다. 즉 사람이 긴장하거나 싸울 경우에 전형적으로 교감신경계가 작용한다. 즉 심장이 뛰거나 소화가 않되거나 동공이 커지는 것 따위가 바로 교감신경계의 역할이라고 할 수 있다. 이 교감신경계에서 말초장기에 보내는 신경이 교감신경이다. 그러므로 심장에서 심장을 신체에 필요에 따라서 많은 일을 하게하는 신경을 차단할 경우에는 협심증을 치료할 수 있게 된다(심장의 산소나 기타 영양분의 수요를 줄인다). |
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| RVR | reduced vascular response; renal vascular resistance; repetitive ventricular response; resistance to... |
|---|---|
| TPR | temperature, pulse, and respiration; testosterone production rate; third party reimbursement; total ... |
| TPVR | total peripheral vascular resistance; total pulmonary vascular resistance |
| MDR | Multi-Drug Resistance |
| PDR | pediatric radiology; peripheral diabetic retinopathy; Physicians' Desk Reference; postdelivery room;... |
| peripheral resistance | The total resistance to flow of blood in the systemic circuit; the quotient produced by dividing the mean arterial pressure by the cardiac minute-volume. Synonym: peripheral resistance. (05 Mar 2000) |
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| chloramphenicol resistance | <microbiology, pharmacology> Nonsusceptibility of a bacterium to the action of chloramphenicol, a potent inhibitor of protein synthesis in the 50s ribosomal subunit where amino acids are added to nascent bacterial polypeptides. (12 Dec 1998) |
| methicillin resistance | Non-susceptibility of a microbe to the action of methicillin, a semi-synthetic penicillin derivative. (12 Dec 1998) |
| multidrug resistance | The insensitivity of various tumours to a variety of chemically related anticancer drugs; mediated by a process of inactivating the drug or removing it from the target tumour cells. (05 Mar 2000) |
| mutual resistance | An interaction between chemicals in which one partially or completelyinhibits the effect of the other (for example, a drug that blocks a hormone's receptor site would be a hormone antagonist). (09 Oct 1997) |
| cross-resistance | <immunology, microbiology> Immunologic resistance to the pathogenic effects of a microorganism because of previous exposure to another species or type having cross reactive antigens. This phenomenon is seen in microbes that acquire resistance to one drug through direct exposure and turn out to have resistance to one or more other drugs to which it has not been exposed. Cross-resistance arises because the mechanism of resistance to several drugs is the same and arises through the identical genetic mutations. (09 Oct 1997) |
| sisomicin-gentamicin resistance ribosomal RNA methylase | <enzyme> Catalyses the methylation of 30s ribosomal units to confer sisomicin-gentamicin resistance in micromonospora zionensis Registry number: EC 2.1.1.- Synonym: sgm gene product, sgm methylase (26 Jun 1999) |
| synaptic resistance | The ease or difficulty with which a nerve impulse can cross a synapse. (05 Mar 2000) |
| systemic vascular resistance | An index of arteriolar compliance or constriction throughout the body; equal to the blood pressure divided by the cardiac output. (05 Mar 2000) |
| dicumarol resistance | A well-defined autosomal dominant resistance to it, over and above general variability in tolerance to the drug. (05 Mar 2000) |
| impact resistance | The ability of a lens for eyewear to withstand impact without shattering or breaking, i.e., of a 3/8 -inch steel ball dropped 50 feet; criteria for determination of impact resistance are specified by U.S. Regulations. (05 Mar 2000) |
| inductive resistance | The weakening of an alternating electric current by passage through a coil of wire or a condenser. Synonym: inductive resistance. (05 Mar 2000) |
| insecticide resistance | The development by insects of resistance to insecticide. (12 Dec 1998) |
| insulin resistance | Many people with noninsulin-dependent diabetes produce enough insulin, but their bodies do not respond to the action of insulin. This may happen because the person is overweight and has too many fat cells, which do not respond well to insulin. Also, as people age, their body cells lose some of the ability to respond to insulin. Insulin resistance is also linked to high blood pressure and high levels of fat in the blood. Another kind of insulin resistance may happen in some people who take insulin injections. They may have to take very high doses of insulin every day (200 units or more) to bring their blood glucose (sugar) down to the normal range. (09 Oct 1997) |
| tetracycline resistance | Nonsusceptibility of a microbe (usually a bacterium) to the action of tetracycline, which binds to the 30s ribosomal subunit and prevents the normal binding of aminoacyl-trna. (12 Dec 1998) |