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autonomously replicating sequence <molecular biology> This is a chromosomal sequence that allows plasmids to replicate on their own in yeast.
(02 Jan 1998)
base sequence <molecular biology> The order of nucleotide bases in a DNA molecule.
(09 Oct 1997)
base sequence analysis <molecular biology> A method, sometimes automated, for determining the base sequence.
(09 Oct 1997)
canonical sequence Of a series of related DNA, RNA or protein sequences, the sequence that reflects the most common choice of base or amino acid at each position. Areas of particularly good agreement often represent conserved functional domains. The generation of consensus sequences has been subjected to intensive mathematical analysis.
(18 Nov 1997)
carbohydrate sequence The sequence of carbohydrates within polysaccharides, glycoproteins, and glycolipids.
(12 Dec 1998)
palindromic sequence <molecular biology> Nucleic acid sequence that is identical to its complementary strand when each is read in the correct direction (e.g. TGGCCA). Palindromic sequences are often the recognition sites for restriction enzymes. Degenerate palindromes with internal mismatching can lead to loops or hairpins being formed (as in tRNA).
(18 Nov 1997)
recognition sequence A nucleotide sequence --typically composed of 4, 6, or 8nucleotides -- that is recognised by a restriction endonuclease. Type II enzymes cut (and theircorresponding modification enzymes methylate) within or very near the recognition sequence.
(09 Oct 1997)
regulatory sequence <molecular biology> DNA sequence to which regulatory molecules such as promotors or enhancers bind, thereby altering the expression of the adjacent gene.
(18 Nov 1997)
centromeric sequence <molecular biology> Special sequences of DNA nucleotides found on chromosomes which provide a site for the attachment of spindle fibres during nuclear division (mitosis or meiosis).
(09 Oct 1997)
chi sequence <molecular biology> A specific sequence of nucleotides on a site on the genome of the bacteria Escherichia coli which strongly encourages recombination and crossing over to occur at that site.
(05 Jan 1998)
PEST sequence Amino acid motif that is thought to target cytoplasmic proteins for rapid proteolytic degradation.
(18 Nov 1997)
molecular sequence data Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as genbank, european molecular biology laboratory (embl), national biomedical research foundation (nbrf), or other sequence repositories.
(12 Dec 1998)
coding sequence The portion of DNA that codes for transcription of messenger RNA.
See: exon.
(05 Mar 2000)
monotonic sequence A sequence in which each value in a set is greater than the preceding value.
(05 Mar 2000)
complementary sequence <molecular biology> Nucleicacid base sequences that can form a double-stranded structure bymatching base pairs, the complementary sequence to G-T-A-C is C-A-T-G.
(09 Oct 1997)
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