| dihydromorphine | <chemical> 4,5-epoxy-17-methylmorphinan-3,6-alpha-diol. A semisynthetic analgesic used in the study of narcotic receptors. It has abuse potential. Pharmacological action: analgesics, opioid, narcotics. Chemical name: Morphinan-3,6-diol, 4,5-epoxy-17-methyl-, (5alpha,6alpha)- (12 Dec 1998) |
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| dihydromorphinone hydrochloride | A synthetic derivative of morphine, with analgesic potency about 10 times that of morphine. Synonym: dihydromorphinone hydrochloride. (05 Mar 2000) |
| dihydroneopterin triphosphate pyrophosphohydrolase | <enzyme> Human liver enzyme removes triphosphate to give 6-pyruvoyl-tetrahydrobiopterin Registry number: EC 3.6.1.- Synonym: 7,8-dihydroneopterin triphosphate phosphate eliminating enzyme, phosphate eliminating enzyme (26 Jun 1999) |
| dihydroorotase | <enzyme> An enzyme that, in the course of pyrimidine biosynthesis, catalyses ring closure by removal of water from N-carbamoyl-l-aspartate to form l-5,6-dihydroorotate (dihydro-orotic acid). Synonym: carbamoylaspartate dehydrase. Chemical name: (S)-Dihydroorotate amidohydrolase Registry number: EC 3.5.2.3 (21 Jun 2000) |
| dihydroorotate dehydrogenase | <enzyme> Converts (s)-dihydroorotate and an aceptor to orotate and a reducted aceptor; dihydro-orotate dehydrogenase was see dihydro-orotate oxidase 1977-93 Registry number: EC 1.3.99.11 Synonym: dihydro-orotate-cytochrome c reductase, dihydro-orotate dehydrogenase (26 Jun 1999) |
| dihydroorotate hydroxylase | <enzyme> A pteridine-requiring enzyme Registry number: EC 1.14.16.- (26 Jun 1999) |
| dihydroorotate oxidase | <enzyme> An enzyme that in the course of pyrimidine biosynthesis, catalyses the oxidation of dihydro-orotic acid to orotic acid utilizing oxygen as the electron acceptor. This enzyme is a flavoprotein which contains both fad and fmn as well as iron-sulfur centres. Chemical name: (S)-Dihydroorotate:oxygen oxidoreductase Registry number: EC 1.3.3.1 (12 Dec 1998) |
| dihydroorotate-ubiquinone oxidoreductase | <enzyme> From bovine liver mitochondria; uses ubiquinone Registry number: EC 1.3.5- Synonym: dihydroorotate dehydrogenase (ubiquinone), dhoo-dehydrogenase-u (26 Jun 1999) |
| dihydroprogesterone | <chemical> 20 alpha-hydroxypregn-4-en-3-one. A naturally occurring progesterone derivative with progestational activity. Chemical name: Pregn-4-en-3-one, 20-hydroxy-, (20S)- (12 Dec 1998) |
| dihydropteridine reductase | <enzyme> An enzyme that catalyses the reduction of 6,7-dihydropteridine to 5,6,7,8-tetrahydropteridine. Chemical name: NAD(P)H:6,7-dihydropteridine oxidoreductase Registry number: EC 1.6.99.7 (12 Dec 1998) |
| dihydropterin oxidase | <enzyme> From drosophila melanogaster; uses a variety of 2-amino-4-oxo-7,8-dihydropteridine cpds as substrates; during reaction 1 mole of molecular o2 is consumed/mole substrate oxidised producing h2o2 Registry number: EC 1.5.3.- (26 Jun 1999) |
| dihydropteroate synthase | <enzyme> An enzyme that catalyses the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate. Chemical name: 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine-diphosphate:4-aminobenzoate 2-amino-4-hydroxydihydropteridine-6-methenyltransferase Registry number: EC 2.5.1.15 (12 Dec 1998) |
| dihydropteroic acid | An intermediate in the formation of folic acid; a compound of 6-hydroxymethylpterin and p-aminobenzoic acid, the combining of which is inhibited by sulfonamides. (05 Mar 2000) |
| dihydropyridine | <drug> For example nifedipine and nitrenidine, specific blockers of some types of calcium channel. (18 Nov 1997) |
| dihydropyridines | Pyridine moieties which are partially saturated by the addition of two hydrogen atoms in any position. (12 Dec 1998) |